Momordicoside K

CAS# 81348-84-7

Momordicoside K

Catalog No. BCN3272----Order now to get a substantial discount!

Product Name & Size Price Stock
Momordicoside K: 5mg $903 In Stock
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Quality Control of Momordicoside K

Number of papers citing our products

Chemical structure

Momordicoside K

3D structure

Chemical Properties of Momordicoside K

Cas No. 81348-84-7 SDF Download SDF
PubChem ID 57330180 Appearance Powder
Formula C37H60O9 M.Wt 648.9
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (3S,7S,8S,9R,10R,13R,14S,17R)-3-hydroxy-17-[(E,2R)-6-methoxy-6-methylhept-4-en-2-yl]-4,4,13,14-tetramethyl-7-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,7,8,10,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-9-carbaldehyde
SMILES CC(CC=CC(C)(C)OC)C1CCC2(C1(CCC3(C2C(C=C4C3CCC(C4(C)C)O)OC5C(C(C(C(O5)CO)O)O)O)C=O)C)C
Standard InChIKey HPSVQEWDZSDXRG-ZMMZJDKESA-N
Standard InChI InChI=1S/C37H60O9/c1-21(10-9-14-33(2,3)44-8)22-13-15-36(7)31-25(45-32-30(43)29(42)28(41)26(19-38)46-32)18-24-23(11-12-27(40)34(24,4)5)37(31,20-39)17-16-35(22,36)6/h9,14,18,20-23,25-32,38,40-43H,10-13,15-17,19H2,1-8H3/b14-9+/t21-,22-,23-,25+,26-,27+,28-,29+,30-,31+,32-,35-,36+,37-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Momordicoside K

The herbs of Mormodica charantia L.

Biological Activity of Momordicoside K

Description1. Momordicoside K has antidiabetic activity.
TargetsAChR

Momordicoside K Dilution Calculator

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Momordicoside K Molarity Calculator

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Preparing Stock Solutions of Momordicoside K

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.5411 mL 7.7053 mL 15.4107 mL 30.8214 mL 38.5267 mL
5 mM 0.3082 mL 1.5411 mL 3.0821 mL 6.1643 mL 7.7053 mL
10 mM 0.1541 mL 0.7705 mL 1.5411 mL 3.0821 mL 3.8527 mL
50 mM 0.0308 mL 0.1541 mL 0.3082 mL 0.6164 mL 0.7705 mL
100 mM 0.0154 mL 0.0771 mL 0.1541 mL 0.3082 mL 0.3853 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Momordicoside K

Novel cucurbitane triterpenoids and anti-cholinesterase activities of constituents from Momordica charantia L.[Pubmed:25115074]

Nat Prod Commun. 2014 Jun;9(6):765-9.

The C-19 epimers of 5beta,19-epoxycucurbita-6,23(E),25(26)-triene-3f,19-diol (1) and 5/,19-epoxy-25-methoxycucurbita-6,23-diene-3beta,19-diol (2) along with (19R,23E)-5beta,19-epoxy-19-methoxycucurbita-6,23,25-trien-3beta-ol (3), (23E)-5beta,19-epoxycucurbita-6,23-diene-3beta,25-diol (4), ligballinol (5), charantin (6) and Momordicoside K(7) were isolated from the green fruits of Momordica charantia. The (S)-epimers of 1 and 2 are the first reports in nature. The acetyl- and butyryl-cholinesterase inhibitory activities of the isolated compounds were evaluated, and 5 showed the highest activity of these compounds against butyrylcholinesterase (IC50 = 32.20 microM) with a reversible and non-competitive inhibition mode.

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