Products for Guanylyl Cyclase
- Cat.No. Product Name Information
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BCC5924
CFM 1571 hydrochloride
Soluble guanylyl cyclase (sGC) activator
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BCC5939
A 350619 hydrochloride
Soluble guanylyl cyclase (sGC) activator
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BCC7912
YC 1
Lificiguat binds to the β subunit of soluble guanylyl cyclase(sGC) with Kd of 0.6-1.1 μM in the presence of CO.
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BCC7204
Guanylin (human)
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BCC6212
NS 2028
NS-2028 is a highly selective soluble Guanylyl Cyclase (sGC) inhibitor with IC50 values of 30 nM and 200 nM for basal and NO-stimulated enzyme activity. NS-2028 inhibits soluble Guanylyl Cyclase activity in homogenates of mouse cerebellum and neuronal NO synthase with IC50 values of 17 nM and 20 nM. NS-2028 inhibits 3-morpholino-sydnonimine (SIN-1)-elicited formation of cyclic GMP in human cultured umbilical vein endothelial cells with an IC50 of 30 nM. NS-2028 is commonly used in the research of nitric oxide signaling pathways, it inhibits NO-dependent relaxant responses in non-vascular smooth muscle completely (1 μM). NS-2028 reduces vascular endothelial growth factor-induced angiogenesis and permeability.
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BCC7932
BAY 41-2272
BAY 41-2272 is a soluble guanylate cyclases (sGC) activator.
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BCC7730
BPIPP
