Products with Anti-allergy bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4056 | Ayanin |
| 1. Ayanin has vasorelaxant activity. 2. Ayanin may have the potential for use in treating allergic asthma. 3. The IC(50) value of Ayanin (quercetin-3,7,4'-O-trimethylether) is 2.2microM for inhibiting interleukin (IL)-4 production from purified basophils. | |
| BCN4291 | Acanthoside B |
| Acanthoside has inhibitory effects on the allergic inflammation. | |
| BCN4494 | Sappanchalcone |
| 1. Sappanchalcone has cytoprotective effect. 2. Sappanchalcone blocks cell cycle progression in the G2/M phase, brazilin inhibited TNFα/NF-κB signaling. 3. Sappanchalcone has anti-inflammatory effect, could be used as an anti-inflammatory and bone-protective agent during the treatment of rheumatoid arthritis. 4. Sappanchalcone suppresses oral cancer cell growth and induces apoptosis through the activation of p53-dependent mitochondrial, p38, ERK, JNK, and NF-κB signaling, could potentially used to treat periodontal, pulpal , periapical inflammatory lesion and oral cancer. 5. Sappanchalcone possesses the most potent effect against allergic reaction in basophilic leukemic (RBL-2H3) cells with an inhibitory concentration (IC50) value of 7.6 uM, it may have anti-allergic activity. 6. Sappanchalcone shows xanthine oxidase inhibitory activity, is a xanthine oxidase inhibitor. | |
| BCN4496 | Dimethylmatairesinol |
| 1. Dimethylmatairesinol can reduce the amount of Immunoglobulin E (IgE) secreted by human myeloma U266 cells, it has potential as an anti-allergic agent. 2. Dimethylmatairesinol exhibits significant cytotoxicity against three human tumor cells(A-549 lung carcinoma, MCF-7 breast adenocarcinoma and HT-29 colon adenocarcinoma ). | |
| BCN4512 | Isoliquiritigenin |
| Isoliquiritigenin has hepatoprotective, chemopreventive, antitumor, vasorelaxant, anti-platelet, anti-allergic, antiviral, antioxidant and anti-inflammatory effects, it can induce growth inhibition and apoptosis through downregulating AA metabolic network and the deactivation of PI3K/Akt in human breast cancer. Isoliquiritigenin also has the ability to protect cells from AA+iron-induced H2O2 production and mitochondrial dysfunction, which is mediated with GSK3β phosphorylation downstream of AMPK. | |
