Products with Anti-cerebral ischemia bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2475 | Dihydrolycorine |
| Dihydrolycorine is an inhibitors of protein synthesis in eukarytic cells, it halts protein synthesis in eukaryotic cells by inhibiting the peptide bone formation step. It protects against anoxia damage of brain in rat.Dihydrolycorine-HCL shows hypotensive effects, it can block alpha 1-adrenoceptors. | |
| BCN2609 | Vinpocetine |
| Vinpocetine is a selective inhibitor of voltage-sensitive sodium channel for the treatment of stroke, vascular dementia and Alzheimer's disease. Vinpocetine can attenuate neointimal formation in diabetic rats and inhibit HG-induced VSMCs proliferation, chemokinesis and apoptotic resistance by preventing ROS activation and affecting MAPK, PI3K/Akt, and NF-κB signaling.Vinpocetine has anti-inflammatory activity, can treat inflammation and pain induced by a gram-negative bacterial component by targeting NF-κB activation and NF-κB-related cytokine production in macrophages. | |
| BCN2742 | Daurinoline |
| Daurinoline is a non-competitive antagonist, it exerts marked relaxation effect on basilar artery of rabbits through non-competitive antagonism, it would have a protective function on microcirculation of cerebral pia mater, which may be beneficial to relieve cerebral ischemic injury. Daurinoline could significantly reverse noradrenaline induced constriction of pial arterioles and venules, and increase the number of blood vessels which were decreased by noradrenaline. | |
| BCN2900 | 3'-Methoxypuerarin |
| 1. 3'-Methoxypuerarin (3'-MOP) can protect hippocampal neurons against ischemia/reperfusion injury by inhibiting apoptosis. 2. 3'-Methoxypuerarin has antioxidant activities, it shows ONOO(-) scavenging activity and weak NO· and O(2)(-) scavenging activities. | |
| BCN2951 | Sodium Dichloroacetate |
| Sodium dichloroacetate is a drug with potential for treating patients with stroke and head injury. Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3; it is cytoprotective to some colorectal cancer cells under hypoxic conditions. | |
