Products with Anti-histamine release bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN1200 | Wogonoside |
| Wogonoside has anticoagulant, anti-inflammatory, anti-angiogenic and anticancer effects, it may exert its anti-inflammatory effect via dual inhibition of NF-κB and NLRP3 inflammasome. Wogonoside induced autophagy through the MAPK-mTOR pathway, it inhibited LTB 4 production at the concentration of 100 uM. | |
| BCN2909 | Bakkenolide D |
| 1. Bakkenolide D has anti-allergic effect. 2. Bakkenolide B and bakkenolide D demonstrates inhibitory effect on the trachea contraction induced by histamine in vitro, they have obvious anti-histamine activities. | |
| BCN4637 | Taxiresinol |
| 1. Taxiresinol shows notable anticancer activity in the in vitro bioassays against colon, liver, ovarian and breast cancer cell lines. 2. Taxiresinol and (7' R)-7'-hydroxylariciresinol can protect the hepatocytes from apoptosis via an inhibition of TNF- alpha production by activated macrophages and a direct inhibition of apoptosis induced by TNF- alpha in D-GalN/LPS-treated mice. 3. Taxiresinol possesses significant antinociceptive activity against p -benzoquinone-induced abdominal contractions. 4. Taxiresinol shows anti-inflammatory activity, it can significantly inhibit carrageenan-induced hind paw edema in mice. 5. Taxiresinol has antiallergic activity, it show inhibitory activity on induced histamine release from the human basophilic cell line, KU812. | |
| BCN5067 | Zeorin |
| 1. Zeorin shows strong inhibition activity against bacteria and fungi. 2. Zeorin markedly exhibits inhibitory activity on histamine release from mast cell induced by DNP24-BSA, it shows potent inhibitory effect by 40% decrease of histamine release. | |
| BCN5795 | Confluentin |
| 1. Confluentin has antimicrobial activity against the gram-positive bacteria. 2. Confluentin significantly inhibits compound 48/80-induced histamine release from rat peritoneal mast cells. 3. Confluentin shows weak cytotoxicity against four human tumor cell lines, HL-60, SMMC-7712, A-549, and MCF-7, in vitro. | |
