Products with Anti-inflammatory bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3183 | Platycodigenin |
| 1. Platycodigenin has in vitro anti-proliferative activity against the HSC-T6 cell line. | |
| BCN3187 | Viscidulin II |
| 1. Viscidulin II can significantly suppress P. acnes-induced IL-8 and IL-1β production in THP-1 cells, concomitant intradermal injection of viscidulin II with P. acnes can effectively attenuate P. acnes-induced ear swelling, and decrease the production of IL-6 and tumor necrosis factor-α in ear homogenates; suggests that it can be potential therapeutic agents against P. acnes-induced skin inflammation. | |
| BCN3188 | Skullcapflavone II |
| Skullcapflavone II is a flavonoid derived from Scutellaria baicalensis, a widely used herbal medicine in anti-inflammatory and anticancer therapy in Korea. Skullcapflavone II may have therapeutic potential for the treatment of allergic asthma. | |
| BCN3194 | Neobavaisoflavone |
| Neobavaisoflavone, exhibits inhibitory activity against DNA polymerase and platelet aggregation, it also has striking anti-inflammatory and anti-cancer effects, Neobavaisoflavone can significantly inhibit the production of reactive oxygen species (ROS), reactive nitrogen species (RNS) and cytokines: IL-1β, IL-6, IL-12p40, IL-12p70, TNF-α in LPS+IFN-γ- or PMA- stimulated RAW264.7 macrophages. | |
| BCN3198 | Corylifol A |
| Corylifol A is a naturally occurring potent inhibitor of hCE2 and UDP-glucuronosyltransferase 1A1 (UGT1A1); it could be the potential uncouplers of neuronal nitric oxide synthase-postsynaptic density protein-95. Corylifol A displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respectively. Corylifol A has antiinflammatory activity, it shows an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells with IC50 values of 0.81 ± 0.15 uΜ, it also inhibits STAT3 phosphorylation induced by IL-6 in Hep3B cells. | |
