Products with Anti-inflammatory bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3149 | Quercetin-3-O-glucuronide |
| Quercetin-3-O-glucuronide is a potent stilbene oxidase inhibitor, it has antioxidant, anti-atherogenic, and anti-inflammatory activities. Quercetin-3-O-glucuronide significantly improves Alzheimer's disease (AD)-type deficits in hippocampal formation basal synaptic transmission and long-term potentiation, possibly through mechanisms involving the activation of the c-Jun N-terminal kinases and the mitogen-activated protein kinase signaling pathways. Quercetin-3-O-glucuronide is equally effective in inhibiting ROS-associated inflammation and ameliorating insulin resistant endothelial dysfunction by beneficial regulation of IRS-1 function. | |
| BCN3158 | Neocryptotanshinone |
| 1. Neocryptotanshinone inhibits rabbit platelet aggregation induced by arachidonic acid. | |
| BCN3164 | Sugiol |
| 1. Sugiol has antioxidant efficacy. 2. Sugiol has significant scavenging activities of 1,1-diphenyl-2-picryl hydrazyl, nitric oxide, superoxide and hydroxyl free radicals. 3. Sugiol's efficacy in inhibiting the inflammatory cytokines of IL-1beta and TNF-alpha could be attributed to a reduction of the ROS that leads to a decrease in the phosphorylation of MAPKs. | |
| BCN3173 | 3-Epiursolic acid |
| 1. 3-Epiursolic acid shows inhibition on Cathepsins L (catL), the IC50 value of 6.5 uM, cathepsins L (catL) and B play an important role in tumor progression and have been considered promising therapeutic targets in the development of novel anticancer agents. 2. 3-Epiursolic acid may have antiinflammatory activity. | |
| BCN3178 | Murrayanol |
| 1. Murrayanol has antioxidant activity. 2. Murrayanol shows an IC50 of 109 μg/mL against hPGHS-1 and an IC50 of 218 μg/mL against hPGHS-2 in antiinflammatory assays. | |
