MurrayanolCAS# 144525-81-5 |
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| Cas No. | 144525-81-5 | SDF | Download SDF |
| PubChem ID | 9975970 | Appearance | Cryst. |
| Formula | C24H29NO2 | M.Wt | 363.5 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 1-[(2E)-3,7-dimethylocta-2,6-dienyl]-7-methoxy-6-methyl-9H-carbazol-2-ol | ||
| SMILES | CC1=C(C=C2C(=C1)C3=C(N2)C(=C(C=C3)O)CC=C(C)CCC=C(C)C)OC | ||
| Standard InChIKey | RTEIBQDXHHQYRJ-CXUHLZMHSA-N | ||
| Standard InChI | InChI=1S/C24H29NO2/c1-15(2)7-6-8-16(3)9-10-19-22(26)12-11-18-20-13-17(4)23(27-5)14-21(20)25-24(18)19/h7,9,11-14,25-26H,6,8,10H2,1-5H3/b16-9+ | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The leaves of Murraya koenigii
| Description | 1. Murrayanol has antioxidant activity. 2. Murrayanol shows an IC50 of 109 μg/mL against hPGHS-1 and an IC50 of 218 μg/mL against hPGHS-2 in antiinflammatory assays. |
| Targets | Topoisomerase | Antifection |
Murrayanol Dilution Calculator
Murrayanol Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.751 mL | 13.7552 mL | 27.5103 mL | 55.0206 mL | 68.7758 mL |
| 5 mM | 0.5502 mL | 2.751 mL | 5.5021 mL | 11.0041 mL | 13.7552 mL |
| 10 mM | 0.2751 mL | 1.3755 mL | 2.751 mL | 5.5021 mL | 6.8776 mL |
| 50 mM | 0.055 mL | 0.2751 mL | 0.5502 mL | 1.1004 mL | 1.3755 mL |
| 100 mM | 0.0275 mL | 0.1376 mL | 0.2751 mL | 0.5502 mL | 0.6878 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Biologically active carbazole alkaloids from Murraya koenigii.[Pubmed:10563914]
J Agric Food Chem. 1999 Feb;47(2):444-7.
The bioassay guided fractionation of the acetone extract of the fresh leaves of Murraya koenigii resulted in the isolation of three bioactive carbazole alkaloids, mahanimbine (1), Murrayanol (2), and mahanine (3), as confirmed from their (1)H and (13)C NMR spectral data. Compound 2 showed an IC(50) of 109 microg/mL against hPGHS-1 and an IC(50) of 218 microg/mL against hPGHS-2 in antiinflammatory assays, while compound 1 displayed antioxidant activity at 33.1 microg/mL. All three compounds were mosquitocidal and antimicrobial and exhibited topoisomerase I and II inhibition activities.
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