Clopidogrel Related Compound ACAS# 144457-28-3 |
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 144457-28-3 | SDF | Download SDF |
| PubChem ID | 9861403 | Appearance | Powder |
| Formula | C15H14ClNO2S | M.Wt | 307.8 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (2S)-2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetic acid | ||
| SMILES | C1CN(CC2=C1SC=C2)C(C3=CC=CC=C3Cl)C(=O)O | ||
| Standard InChIKey | DCASRSISIKYPDD-AWEZNQCLSA-N | ||
| Standard InChI | InChI=1S/C15H14ClNO2S/c16-12-4-2-1-3-11(12)14(15(18)19)17-7-5-13-10(9-17)6-8-20-13/h1-4,6,8,14H,5,7,9H2,(H,18,19)/t14-/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Clopidogrel Related Compound A is a impurity from Clopidogrel. |
| Structure Identification | Der Pharma Chemica;2010,2(4):244.Non chiral High Performance Liquid Chromatography method for monitoring unknown impurities generated during stability of Clopidogrel tablets[Reference: WebLink]The purpose of this study was to develop a High performance liquid chromatography (HPLC) method for separating the unknown impurities generated during the accelerated stability storage of Clopidogrel Bisulphate Tablets. Also, we used the newly developed method to identify the factors that contribute to the formation of these unknown impurities in the tablet formulation. |
Clopidogrel Related Compound A Dilution Calculator
Clopidogrel Related Compound A Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.2489 mL | 16.2443 mL | 32.4886 mL | 64.9773 mL | 81.2216 mL |
| 5 mM | 0.6498 mL | 3.2489 mL | 6.4977 mL | 12.9955 mL | 16.2443 mL |
| 10 mM | 0.3249 mL | 1.6244 mL | 3.2489 mL | 6.4977 mL | 8.1222 mL |
| 50 mM | 0.065 mL | 0.3249 mL | 0.6498 mL | 1.2995 mL | 1.6244 mL |
| 100 mM | 0.0325 mL | 0.1624 mL | 0.3249 mL | 0.6498 mL | 0.8122 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Non chiral High Performance Liquid Chromatography method for monitoring unknown impurities generated during stability of Clopidogrel tablets
Der Pharma Chemica;2010, Vol. 2 Issue 4, p244
The purpose of this study was to develop a High performance liquid chromatography (HPLC) method for separating the unknown impurities generated during the accelerated stability storage of Clopidogrel Bisulphate Tablets. Also, we used the newly developed method to identify the factors that contribute to the formation of these unknown impurities in the tablet formulation. Study was carried out by incubation of mixture of excipients and Clopidogrel API in 5:1 ratio at 80°C for 3days. The new HPLC method was developed by using Kromasil 100 C18 column and using gradient method with mobile phase of 0.1% Triflouroacetic acid in water in pump A and 0.1% Trifluoroacetic acid in Acetonitrile in pump B was suitable for separating the unknown impurities from the Clopidogrel Related Compound A.
