Products with Anti-inflammatory bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN6677 | 4-O-Methylbutein |
| 1. 4-O-Methylbutein (2',3,4'-trihydroxy-4-methoxychalcone) is a potent heme oxygenase-1 (HO-1) inducer, the upregulation of HO-1 has proven to be a useful tool for fighting inflammation,suggests that 4-O-methylbutein may have anti-inflammation activity. | |
| BCN6679 | Licoricidin |
| 1. The hexane-ethanol extract of Glycyrrhiza uralensis, which contains licoricidin, is a potent anti-metastatic agent, which can markedly inhibit the metastatic and invasive capacity of malignant prostate cancer cells. 2. Licoricidin inhibits lung metastasis of 4T1 mammary carcinoma cells, which may be mediated via inhibition of cancer cell migration, tumor angiogenesis, and lymphangiogenesis. 3. Licoricidin and licorisoflavan A are effective in inhibiting the growth of all three bacterial species(Porphyromonas gingivalis, Prevotella intermedia and Solobacterium moorei), with minimal inhibitory concentrations in the range of 2-80 ug /ml, they have a potential for reducing bacterial volatile sulfur compounds (VSCs) production and therefore for controlling halitosis. 4. Licoricidin blocks UVA-induced photoaging via ROS scavenging,this activity converges to limit the activity of MMP-1, suggests that licoricidin may be considered as an active ingredient in new topically applied anti-ageing formulations. 5. Licoricidin and licorisoflavan A have potential for the development of novel host-modulating strategies for the treatment of cytokine and/or MMP-mediated disorders such as periodontitis. | |
| BCN6685 | Zanthobungeanine |
| 1. Zanthobungeanine shows the inhibitory action on the development of A549 cell only in high concentration and has no antipersonnel effect on A549 cell. 2. Zanthobungeanine has anti-inflammatory activity, it shows moderate NO production inhibitory activity with an IC50 value of 37.26 mg /L. 3. Zanthobungeanine shows obviously inhibitoryactivity to platelet aggregation caused by platelet-activating factor (PAF). | |
| BCN6689 | Sideritoflavone |
| 1. Sideritoflavone has anti-inflammatory effect , it is a selective inhibitor of lipoxygenase activity in vitro. | |
| BCN6722 | Xanthyletin |
| 1. Xanthyletin exhibits potent inhibition (IC50 values ≤ 4.79 ug/mL) of superoxide anion generation by human nutrophils in response to N-formyl-L-methionyl-L-leucyl-L-phenylalanine/cytochalasin B (fMLP/CB). 2. Xanthyletin inhibits fMLP/CB-induced elastase release with IC50 values ≤ 5.48 ug/mL. 3. Xanthyletin is an inhibitor of symbiotic fungus (Leucoagaricus gongylophorus) of leaf-cutting ant (Atta sexdens rubropilosa). 4. Xanthyletin has anti-inflammatory activity, it displays potent nitric oxide (NO)-reducing activity in microglial cells. | |
