Products with Anti-inflammatory bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN6487 | Heliangin |
| 1. Heliangin shows anti-inflammatory effects, it can inhibit lipopolysaccharide-induced inflammation through signaling NF-κB pathway on LPS-induced RAW 264.7 cells. 2. Heliangin exhibits cytotoxicity against human oral epidermoid (KB), cervical epitheloid (Hela), and liver (hepa59T/VGH) carcinoma cells. | |
| BCN6501 | Euphohelioscopin A |
| 1. Euphohelioscopin A exhibits moderate inhibitory activity on the release of cytokine TNF-α (IC50 = 23.7 ± 1.7 uM), IL-6 (IC50 = 46.1 ± 1.1 uM) and chemokine MCP-1 (IC50 = 33.7 ± 3.8 uM) in lipopolysaccharide (LPS) induced RAW 264.7 macrophages without notable cytotoxicity (IC50 > 80 uM). 2. Euphohelioscopin A, an activator of protein kinase C (PKC), it inhibits proliferation and induces differentiation of the myeloid leukemia cell lines THP-1 and HL-60. | |
| BCN6505 | Juglanin |
| Juglanin has anti-tumor, antioxidant,and hepatoprotective activities. Juglanin shows protective effects on fructose-induced hepatitis by inhibiting inflammation and apoptosis through TLR4 and JAK2/STAT3 signaling pathways in fructose-fed rats. Juglanin can lead to G2/M phase arrest, induce apoptosis as well as autophagy through the ROS/JNK signaling pathway in human breast cancer cells | |
| BCN6508 | Demethylsuberosin |
| 1. Demethylsuberosin displays suppressive effects on LPS-induced NO and PGE2 production with the IC50 value of 9.42 uM, suggests that it has potential anti-inflammatory activity. | |
| BCN6509 | Akuammidine |
| 1. Akuammidine shows anti-inflammatory and anti-asthmatic properties. 2. Akuammidine has opioid analgesic activity, it shows a preference for mu-opioid binding sites with Ki values of 0.6, 2.4 and 8.6 microM at mu-, delta- and kappa-opioid binding sites, respectively. | |
