Products with Anti-inflammatory bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4899 | Coniferaldehyde |
| 1. Coniferaldehyde exerts anti-inflammatory properties by inducing heme oxygenase-1(HO-1), it inhibits LPS-induced apoptosis through the PKC α/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells. 2. Coniferaldehyde can significantly inhibit the growth of viability of strains of Oenococcus oeni . | |
| BCN4901 | Cannabichromene |
| 1. Cannabichromene is a major non-psychotropic phytocannabinoid that inhibits endocannabinoid inactivation and activates the transient receptor potential ankyrin-1 (TRPA1), it selectively reduces inflammation-induced hypermotility in vivo in a manner that is not dependent on cannabinoid receptors or TRPA1. 2. Cannabichromene exerts anti-inflammatory actions in activated macrophages with tonic CB1 cannabinoid signalling being negatively coupled to this effect and ameliorates experimental murine colitis. 3. Cannabichromene can raise the viability of neural stem progenitor cells (NSPCs), while inhibiting their differentiation into astroglia, possibly through up-regulation of ATP and adenosine signalling. | |
| BCN4909 | Gentiopicroside |
| Gentiopicroside has been developed into a novel traditional Chinese drug named gentiopicroside injection, and it was approved for the treatment of acute jaundice and chronic active hepatitis by SFDA.Gentiopicroside has analgesic, smooth muscle relaxing, antibacterial, and free radical scavenging activities, it exerts anti-inflammatory effects on experimental acute colitis through attenuating the expression levels of TNF-α, IL-1β, IL-6, iNOS and COX-2. | |
| BCN4911 | Berberine |
| Berberine has neuroprotective, antidepressant, antineoplastic, and anti- fibrosis activities; it is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism, it may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS; it also may be one of the targeted therapeutic agents that can restore barrier function in intestinal disease states.Berberine is used in histology for staining heparin in mast cells. As a natural dye, berberine has a colour index of 75160. | |
| BCN4925 | Agrimonolide |
| 1. Agrimonolide exerts anti-inflammatory activity, at least in part, via suppressing LPS-induced activation of JAK-STATs and p38 MAPKs signaling pathway. 2. Agrimonolide is a potential α1 adrenergic receptor antagonist . 3. Agrimonolide and desmethylagrimonolide can effectively increase insulin-mediated glycogen level in heptocytes, they may play an important role in regulating glucose metabolism in insulin-resistance HepG2 cells and could be developed as a promising natural material for diabetes prevention and treatment. | |
