Products with Anti-inflammatory bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4703 | Myricetin 3-O-galactoside |
| Myricetin 3-O-galactoside has cytotoxicity, antioxidant, anti-genotoxic, antinociceptive and anti-inflammatory effects, the effects are related to peripheral inhibition of nitric oxide synthesis, mainly inducible nitric oxide synthase (iNOS). | |
| BCN4725 | Sulfuretin |
| 1. Sulfuretin may have therapeutic value in preventing or delaying the progression of rheumatoid arthritis. 2. Sulfuretin has therapeutical effect on leukemia, due to its potent apoptotic activity through the extrinsic pathway driven by a Fas-mediated caspase-8-dependent pathway. 3. Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 through the Nrf2/ARE and JNK/ERK signaling pathways. 4. Sulfuretin may have a potential role for neuroprotection, possibly through inhibition of phosphorylation of MAPK, PI3K/Akt, and GSK-3β, which leads to mitochondrial protection, NF-κB modulations and subsequent suppression of apoptosis via ROS-dependent pathwaysand, may be used as a therapeutic agent for PD. | |
| BCN4732 | Narciclasine |
| 1. Narciclasine displays marked proapoptotic and cytotoxic activity, as does pancratistatin, and significant in vivo anticancer effects in various experimental models, but it is also associated with severe toxic side effects. 2. Narciclasine acts on the auxin signaling pathway upstream of TIR1, which modulates Aux/IAA protein degradation, and thereby affects the auxin-mediated responses in Arabidopsis roots, inhibits the root hair development of lettuce seedlings. 3. The alkaloid Narciclasine is the bioactive compound responsible for the anti-inflammatory action of HCE. | |
| BCN4770 | Lasiodiplodin |
| 1. Lasiodiplodin inhibits electron transport chain. 2. Lasiodiplodin shows moderate suppression effects on induced NO production, suggest that it may have potential anti-inflammatory activity. | |
| BCN4788 | Warangalone |
| 1. Warangalone shows significant cytotoxicity against HL-60 cells. 2. Warangalone with cAK may contribute to its biological effects in vivo and to the insecticidal activity of the plant D. scandens. 3. Warangalone is a powerful inhibitor of protein kinase A, shows marked effectiveness as an anti-inflammatory on the phospholipase A(2)-induced paw edema and on the 12-O-tetradecanoylphorbol 13-acetate-induced ear edema in mice, after systemic and local administration, respectively. | |
