Products with Anti-inflammatory bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5058 | Antidesmone |
| 1. Antidesmone is a relative toxic anti-inflammatory drug, it can inhibit inflammation on stimulated macrophages and thereby prevents acute lung injury by regulating MAPK and NF-κB signaling pathways. 2. Antidesmone exhibits potent antitrypanosomal activity against Trypanasoma cruzi, the pathogenic agent of Chagas disease. 3. Antidesmone is a selective post-emergent herbicide probe at 300μM by reducing the biomass production of Physalis ixacarpa plants, it also behaves as pre-emergent herbicide due to inhibit Physalis ixacarpa plant growth about 60%. | |
| BCN5059 | Evodol |
| 1. Evodol and limonin possess larvicidal activity against the Asian tiger mosquitoes with LC50 values of 52.22 and 32.43 ug/ml, respectively. 2. Evodol shows inhibitory activity on nitric oxide (NO) production in lipopolysaccharide -activated RAW264.7 macrophages, suggests that it may as an anti-inflammatory agent or lead compound. | |
| BCN5060 | 9-Hydroxy-alpha-lapachone |
| 1. 9-Hydroxy-alpha-lapachone can highly inhibit the growth of H. pylori , it exhibits potent inhibitory activity against H. pylori Cystathionine gamma-synthase, with IC(50) values of 4.64 microM. 2. 9-Hydroxy-alpha-lapachone exhibits potent inhibitory effects on lipopolysaccharide- induced NO synthesis in RAW 264.7 cells, with IC50 values of 4.64 microM, suggests that it may have anti-inflammatory activity. | |
| BCN5080 | Strictosamide |
| 1. Strictosamide may have important effects on inflammation and inflammatory pain. 2. Strictosamide is slightly toxic to Charles River mouse (LD(50)=723.17 mg/kg), producing CNS depression and kidney toxicity. 3. Strictosamide has nonsignificant in vitro and in vivo effect on kidney Na(+),K(+)-ATPase activity but produced an in vivo increase of Na(+),K(+)-ATPase activity of brain. 4. Strictosamide possesses antibacterial and antiviral activities. | |
| BCN5092 | Meranzin |
| 1. Meranzin hydrate can induce similar effect to Fructus Aurantii on intestinal motility and it was, at least in part, mediated by stimulation of H1 histamine receptors. 2. Meranzin exhibits strong anti-inflammatory and analgesic activity. | |
