Products with
Anti-inflammatory bioactivity
Cat.No.
|
Product Name
|
BCN5291 |
Ziyuglycoside II
|
Ziyuglycoside II has a wide range of clinical applications including hemostasis, antibiosis, anti-inflammation and anti-oxidation. Ziyuglycoside II has inhibitory effect on the growth of MDA-MB-435 cells, it induces cell cycle arrest and apoptosis through activation of ROS/JNK pathway in human breast cancer cells.Ziyuglycoside II methyl ester possess improved anti-diabetic properties, and has hepato-renal protective activities in type 2 diabetes. |
BCN5294 |
Norathyriol
|
1. Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.
2. Norathyriol can improve the glucose utilization and insulin sensitivity by up-regulation of the phosphorylation of AMPK.
3. Norathyriol exerts a potent chemopreventive activity by inhibiting Akt activation in neoplastic cell transformation.
4. Norathyriol as a safe new chemopreventive agent that is highly effective against development of UV-induced skin cancer.
5. Norathyriol may be a dual, yet weak, cyclooxygenase and lipoxygenase pathway blocker, it has anti-inflammatory effect, and has inhibitory effect on the A23187-induced pleurisy and acetic acid-induced writhing response in mice.
6. Norathyriol can relax the rat thoracic aorta mainly by suppressing the Ca2+ influx through both voltage-dependent and receptor-operated calcium channels. |
BCN5298 |
Mesuaxanthone A
|
1. Mesuaxanthone A and mesuaxanthone B are two yellow pigments.
2. Mesuaxantbone A and mesuaxanthone B produce varying degrees of C.N.S. depression characterised by ptosis, sedation, decreased spontaneous motor activity, loss of muscle tone, potentiation of pentobarbitone sleeping time and ether anaerthesia in mice and rats; they also exhibit anti inflammatory activity both by intraperitoneal and oral routes in rats. |
BCN5309 |
Vestitol
|
Vestitol is a phytoalexin with insect feeding-deterrent activity, it has antioxidant, anti-inflammatory and antimicrobial activities, it can inhibit neutrophil migration at a dose of 10 mg/kg, and shows MICs ranging from 25-50 to 50-100 ug/mL and MBCs ranging from 25-50 to 50-100 ug/mL.Vestitol exerts a limited inhibitory effect on S. hermonthica germination, it can significantly inhibit seedling growth, it also contributes, at least in part, to the host's defence mechanism and acts as a chemical barrier against the intrusion of the parasite. |
BCN5310 |
Ligustroside
|
1. Ligustroside shows little antioxidant activity.
2. Ligustroside shows moderate antiviral activities against parainfluenza type 3 virus.
3. Ligustroside has anti-inflammatory properties, it shows a significant inhibition effect on prostaglandin E2 (PGE2)-release. |