Products with Anti-leishmanial bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2773 | Tomatidine |
| Tomatidine shows antibiotic, and anti-inflammatory activities, it significantly suppresses the activity of ACAT and leads to reduction of atherogenesis. Tomatidine inhibits the invasion of A549 cells by reducing the expression of MMPs, also inhibits ERK and Akt signaling pathways and NF-κB activity, suggests a new therapeutic potential for Tomatidine in anti-metastatic therapy. | |
| BCN3060 | 5-Galloylquinic acid |
| 5-Galloylquinic acid as an index for the baking intensity of oolong teas. It has antioxidant activity. | |
| BCN3330 | Trametenolic acid |
| 1. Trametenolic acid is a cytotoxic agent. 2. Trametenolic acid and Betulin as a new candidate of potent tyrosinase inhibitors, can decrease tyrosinase activity and melanin content. 3. Trametenolic acid exhibits a mode of mixed inhibition with a K I of 0.9 μM, K IS of 0.5 μM, and an IC50 of 7.25 μM. | |
| BCN3468 | Skimmianin |
| 1. Skimmianine is a new inhibitor against the Leishmania APRT enzyme. 2. Skimmianine has a selective inhibitory effect on the 5-hydroxytryptamine-induced vasopressor responses of rats. 3, Skimmianine is a strong acetylcholinesterase (AChE) inhibitor. 4. Skimmianine has anti-inflammatory properties. 5. Skimmianine has leishmanicidal effect , it is thus a promising drug candidate for L. braziliensis due to its potent immunomodulatory activity. | |
| BCN3746 | Corynantheine |
| 1. Corynantheine shows pronounced activity against Leishmania major promastigotes (IC50 at the micromolar level) but no significant in vitro antiplasmodial activity (against chloroquinesensitive Plasmodium falciparum). | |
