Products with Anti-melanogenic bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5741 | Isosaxalin |
| 1. Isosaxalin, heraclenin and heraclenol 3'-Me ether have melanin biosynthesis inhibitory activities . | |
| BCN5916 | Saikosaponin B2 |
| Saikosaponin B2 as an efficient inhibitor of early HCV entry, including neutralization of virus particles, preventing viral attachment, and inhibiting viral entry/fusion. It (5 microM) induces differentiation of B16 melanoma cells, with potentiation of expressions of melanogenesis and tyrosinase. | |
| BCN6085 | Fupenzic acid |
| 1. Fupenzic acid shows a significant decrease in intracellular melanin content in B16-F10 cells, and in culture media melanin. | |
| BCN6222 | Ergosterol peroxide glucoside |
| 1. Ergosterol peroxide exhibits inhibitory effects on human breast adenocarcinoma MCF-7 cells, it inhibits the growth of MCF-7 cells by inducing cell apoptosis. 2. Ergosterol peroxide exhibits hACAT-1 and Lp-PLA2 inhibitory effects, with inhibitory values of 51.6 +/- 0.9 and 51.7 +/- 1.2%, at a treatment concentration of 0.23 mM; suggests that it could as an anti-atherosclerosis agent. 3. Ergosterol peroxide shows very strong anticomplementary activity on the classical pathway, the IC(50) values being 5.0 muM. 4. Ergosterol peroxide can suppress inflammatory responses in RAW264.7 macrophages and growth of HT29 colon adenocarcinoma cells, it appears to suppress cell growth and STAT1 mediated inflammatory responses by altering the redox state in HT29 cells. 5. Ergosterol peroxide has anti-melanogenic activity. 6. Ergosterol peroxide has amoebicidal activity (IC50 =4.23nM), it produces a strong cytotoxic effect against amoebic growth. 7. Ergosterol peroxide has osteoclastogenesis inhibitory effect, it shows an inhibitory effect in a dose-dependent manner and an inhibition rate of up to 62% with low cytotoxicity, even at a concentration as low as 1.0 microg/mL. 8. Ergosterol peroxide has antibacterial activity against Mycobacterium tuberculosis and has antiviral action. 9. Ergosterol peroxide has anti-oxdiant activity. | |
| BCN6307 | Arbutin |
| Arbutin is a tyrosinase inhibitor with an IC50 of 1.09 mM, which has gastroprotective, whitening, anti- age, anti-oxidant , anti-inflammatory, a depigmenting effects and UVB/ UVC filter. Arbutin has mutagenicity in mammalian cells after activation by human intestinal bacteria. | |
