Products with Anti-melanogenic bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5095 | Epitulipinolide |
| 1. Epitulipinolide has antitumor activity. 2. Epitulipinolide diepoxide has antioxidative activity and chemopreventive activity in skin melanoma cells, it can significantly inhibit the proliferation of melanoma cells. | |
| BCN5234 | Heraclenol |
| 1. Heraclenol is a germination inhibitor in the parsley seeds. 2. Heraclenol has anti-inflammatory properties against the ear edema in mice produced by TPA. 3. Heraclenol and heraclenin inhibit the proliferation of melanoma cells and cell cycle at G2/M at concentrations of 0.1-1.0 uM. | |
| BCN5255 | 8-Deoxygartanin |
| 1. 8-Deoxygartanin inhibits p65 activation with IC50 values of 11.3 microM. 2. 8-Deoxygartanin has cytotoxic effect on human melanoma cells, it is a potential candidate as anti-melanoma agents. 3. 8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor. 4. 8-Deoxygartanin exhibits significant inhibition of self-induced β-amyloid (Aβ) aggregation, it has multifunctional activities against Alzheimer's disease (AD) and could be promising compounds for the therapy of AD. 5. 8-Deoxygartanin has antiplasmodial activity against the W2 strain of Plasmodium falciparum which is resistant to chloroquine and other antimalarial drugs. 6. 8-Deoxygartanin at 5 ug/ml can increase the cell cycle arrest in G(1) phase compared with untreated cells . | |
| BCN5415 | Isobavachalcone |
| Isobavachalcone has anti-cancer, anthelmintic, antibacterial, aphrodisiac, anti-inflammatory, astringent and antiplatelet activities, Isobavachalcone can induce apoptotic cell death in neuroblastoma via the mitochondrial pathway; it can significantly inhibit both oligomerization and fibrillization of Aβ42; it can suppress inducible nitric oxide synthase (iNOS) expression induced by macrophage-activating lipopeptide 2-kDa, polyriboinosinic polyribocytidylic acid, or lipopolysaccharide. | |
| BCN5418 | Methylophiopogonanone B |
| Methylophiopogonanone B has inhibition of hypoxia-inducible factor (HIF)-1 alpha activity.Methylophiopogonanone B can inhibit melanosome transfer to keratinocytes as well as melanocyte dendrite outgrowth, it also suppress pigmentation in a three-dimensional skin culture model through the inhibition of melanocyte dendrite outgrowth, it could result in the creation of very unique cosmetic products that would precisely control the darkening or lightening of skin tone. | |
