EpitulipinolideCAS# 24164-13-4 |
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| Cas No. | 24164-13-4 | SDF | Download SDF |
| PubChem ID | 5322173 | Appearance | Powder |
| Formula | C17H22O4 | M.Wt | 290.4 |
| Type of Compound | Sesquiterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | [(6E,10E)-6,10-dimethyl-3-methylidene-2-oxo-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-4-yl] acetate | ||
| SMILES | CC1=CC2C(C(CC(=CCC1)C)OC(=O)C)C(=C)C(=O)O2 | ||
| Standard InChIKey | UPNVKIZABMRHNR-BBYAVRKXSA-N | ||
| Standard InChI | InChI=1S/C17H22O4/c1-10-6-5-7-11(2)9-15-16(12(3)17(19)21-15)14(8-10)20-13(4)18/h6,9,14-16H,3,5,7-8H2,1-2,4H3/b10-6+,11-9+ | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The barks of Liriodendron chinense (Hemsl.) Sarg.
| Description | 1. Epitulipinolide has antitumor activity. 2. Epitulipinolide diepoxide has antioxidative activity and chemopreventive activity in skin melanoma cells, it can significantly inhibit the proliferation of melanoma cells. |
Epitulipinolide Dilution Calculator
Epitulipinolide Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.4435 mL | 17.2176 mL | 34.4353 mL | 68.8705 mL | 86.0882 mL |
| 5 mM | 0.6887 mL | 3.4435 mL | 6.8871 mL | 13.7741 mL | 17.2176 mL |
| 10 mM | 0.3444 mL | 1.7218 mL | 3.4435 mL | 6.8871 mL | 8.6088 mL |
| 50 mM | 0.0689 mL | 0.3444 mL | 0.6887 mL | 1.3774 mL | 1.7218 mL |
| 100 mM | 0.0344 mL | 0.1722 mL | 0.3444 mL | 0.6887 mL | 0.8609 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Antioxidant and anticancer constituents from the leaves of Liriodendron tulipifera.[Pubmed:24705566]
Molecules. 2014 Apr 3;19(4):4234-45.
Sixteen compounds were extracted and purified from the leaves of Liriodendron tulipifera. These compounds include aporphines, oxoaporphine, coumarin, sesquiterpene lactone, benzenoids, cyclitol and steroids. (+)-Norstephalagine (2) (an aporphine) and scopoletin (8) (a coumarin) were isolated from Liriodendron tulipifera leaves from the first time. The identified compounds were screened for their antiradical scavenging, metal chelating and ferric reducing power activities. The results have showed that these compounds have antioxidative activity. The study has also examined the chemopreventive property of the isolated compounds against human melanoma cells A375. The results shown that (-)-anonaine (1), (-)-liridinine (3), (+)-lirinidine (6), lysicamine (7) and Epitulipinolide diepoxide (9) significantly inhibited the proliferation of melanoma cells. These results revealed that these compounds have antioxidative activity and chemopreventive activity in skin melanoma cells.
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