Isosaxalin

CAS# 55481-86-2

Isosaxalin

Catalog No. BCN5741----Order now to get a substantial discount!

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Isosaxalin: 5mg $690 In Stock
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Quality Control of Isosaxalin

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Chemical structure

Isosaxalin

3D structure

Chemical Properties of Isosaxalin

Cas No. 55481-86-2 SDF Download SDF
PubChem ID 91885198 Appearance Powder
Formula C16H15ClO5 M.Wt 322.7
Type of Compound Coumarins Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 9-[(2R)-3-chloro-2-hydroxy-3-methylbutoxy]furo[3,2-g]chromen-7-one
SMILES CC(C)(C(COC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2)O)Cl
Standard InChIKey VNNTVHKCIBWHDR-LLVKDONJSA-N
Standard InChI InChI=1S/C16H15ClO5/c1-16(2,17)11(18)8-21-15-13-10(5-6-20-13)7-9-3-4-12(19)22-14(9)15/h3-7,11,18H,8H2,1-2H3/t11-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Isosaxalin

The roots of Angelica polymorpha Maxim.

Biological Activity of Isosaxalin

Description1. Isosaxalin, heraclenin and heraclenol 3'-Me ether have melanin biosynthesis inhibitory activities .

Isosaxalin Dilution Calculator

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Isosaxalin Molarity Calculator

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Preparing Stock Solutions of Isosaxalin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.0989 mL 15.4943 mL 30.9885 mL 61.9771 mL 77.4713 mL
5 mM 0.6198 mL 3.0989 mL 6.1977 mL 12.3954 mL 15.4943 mL
10 mM 0.3099 mL 1.5494 mL 3.0989 mL 6.1977 mL 7.7471 mL
50 mM 0.062 mL 0.3099 mL 0.6198 mL 1.2395 mL 1.5494 mL
100 mM 0.031 mL 0.1549 mL 0.3099 mL 0.6198 mL 0.7747 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Isosaxalin

Melanin biosynthesis inhibitory activities of coumarins isolated from Angelica polymorpha MAXIM

Korean Journal of Microbiology & Biotechnology, 2003 , 47 (12) :3829-36.

During the screening for inhibitors of melanin biosynthesis from plant extract, Angelica polymorpha MAXIM which showed a high lecel of inhibition was selected. The inhibiting substances were purified form methanol extract of Angelica Polymorpha MAXIM followed by silica gel column chromatography and HPLC. The inhibitors were identified as heraclenin, Isosaxalin and heraclenol 3'-Me ether , by spectroscopic methods of ESI-MS, ©öH-NMR,©ö©øC-NMR, DEPT, HMQC and HMBC. These compounds did not have mushroom tyrosinase inhibitory activity, but showed a highly potent melanin biosynthesis inhibition zone in the plate culture of Streptomyces bikiniensis, a bacterium used as an indicator organism in this work. These compounds did not show any growth inhibition against S. bikiniensis at the same concentration of melanin biosynthesis test

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