Products with Antiasthmatic bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN1660 | 3-O-Methylquercetin |
| 1. 3-O-Methylquercetin may exert its anti-inflammatory effect through the inhibition of iNOS DNA transcription. 2. 3-O-Methylquercetin is a selective and competitive PDE3/PDE4 inhibitor, and inhibits PDE3 than PDE4 with a low K(m) value. 3. 3-O-Methylquercetin inhibits total cAMP- and cGMP-phosphodiesterase (PDE) of guinea pig trachealis at low concentrations. 4. 3-O-Methylquercetin has both anti-inflammatory and bronchodilating effects, and has the potential for use in the treatment of asthma at a dose without affecting blood pressure. 5. 3-O-Methylquercetin has antiviral activity. | |
| BCN2182 | Roflumilast |
| 1. Roflumilast is a phosphodiesterase 4 inhibitor that may improve lung function and reduce the frequency of exacerbations in patients with COPD. 2. Suppression of hematological and immunological markers of inflammation and enhanced apoptosis in animals treated with Roflumilast points to the possibility of a beneficial effect of Roflumilast in allergic inflammation. 3. Roflumilast has anti-inflammatory and immunomodulatory potential,it will be useful in the treatment of chronic inflammatory disorders such as asthma and chronic obstructive pulmonary disease. | |
| BCN2996 | Sappanone A |
| 1. Sappanone A is the first homoisoflavanone to be discovered with melanogenesis inhibitory activity. 2. Sappanone A exerts its anti-inflammatory effect by modulating the Nrf2 and NF-κB pathways, and may be a valuable compound to prevent or treat inflammatory diseases. | |
| BCN3035 | Ganoderic acid C1 |
| 1. Ganoderic acid C1 inhibits histamine release. 2. Ganoderic acid C1 has anti-tumor-promoting activity. 3. Ganoderic acid C1 is moderately active inhibitors against HIV-1 protease. 4. Ganoderic acid C1 has anti-inflammatory activity, has potential for treating TNF-α mediated inflammation in asthma and other inflammatory diseases. | |
| BCN3188 | Skullcapflavone II |
| Skullcapflavone II is a flavonoid derived from Scutellaria baicalensis, a widely used herbal medicine in anti-inflammatory and anticancer therapy in Korea. Skullcapflavone II may have therapeutic potential for the treatment of allergic asthma. | |
