Products with Antibacterial bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5721 | Decarine |
| 1. Decarine has high antibacterial activity against mycobacterial, gram-positive and gram-negative bacteria, and low cytotoxicity towards human macrophages. 2. Decarine inhibits fMLP/CB-induced elastase release with IC(50) values < or = 5.53 microg/mL. | |
| BCN5730 | Galangin |
| Galangin is an agonist/antagonist of the arylhydrocarbon receptor, and also shows inhibition of CYP1A1 activity. Galangin has anti-proliferation, anti-metastatic, anti-inflammatory, vasorelaxant, antiviral, anti-allergic inflammatory,anti-obesity effects; it may be a potential candidate for the treatment of vitiligo. Galangin can inhibit Topo I activity and reduce the unwinding rate of single stranded DNNA in tumor cells, which plays an important role in induction of A549 and H46 cell apoptosis. Galangin shows an inhibitory effect on acetylcholinesterase (AChE) activity with the IC(50) of 120 microM; it also inhibits ERK, NF-κB-p65 and proinflammatory gene expression. | |
| BCN5759 | Hinokiol |
| 1. Hinokiol demonstrates potent activity against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA). 2. Hinokiol has significant inhibitory effects on 5-hydroxy-eicosa-tetra-enoic acid (5-HETE) and leukotriene B(4) (LTB4) formations, suggests that it has anti-inflammatory activity. | |
| BCN5766 | Platyphyllenone |
| 1. Platyphyllenone has shown promising anti-filarial activity both in vitro and in vivo studies. 2. Platyphyllenone and hirsutenone can inhibit the biosynthesis of violacein in C. violaceum CV026. | |
| BCN5795 | Confluentin |
| 1. Confluentin has antimicrobial activity against the gram-positive bacteria. 2. Confluentin significantly inhibits compound 48/80-induced histamine release from rat peritoneal mast cells. 3. Confluentin shows weak cytotoxicity against four human tumor cell lines, HL-60, SMMC-7712, A-549, and MCF-7, in vitro. | |
