Products with Anticancer bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4509 | Guajadial |
| 1. Guajadial, psidial A and psiguadials A and B can reduce tumor growth and stimulate uterus proliferation, suggest that they may act as Selective Estrogen Receptors Modulators (SERMs), therefore holding significant potential for anticancer therapy. 2. Guajadial shows α-glucosidase inhibitory activities significantly and its activity was better than that of Acarbose. 3. Guajadial exhibits potent inhibitory effects on the growth of human hepatoma cells. | |
| BCN4521 | Aristolactam AIIIa |
| 1. Aristolactam AIIIa has anti-tumor activity. 2. Aristolactam AIIIa was identified as a new type of Plk1 inhibitors, targeting the Polo Box domain (PBD). 3. Aristolactam IIIa shows inhibition of platelet aggregation induced by collagen or arachidonic acid. | |
| BCN4530 | Leachianone A |
| Leachianone A is a potential antitoxic agent, it shows inhibitory effects on cadmium- Induced cytotoxicity. Leachianone A exhibits inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2); leachianone A also possesses a profound cytotoxic activity against human hepatoma cell line HepG2 in vitro, with an IC(50) value of 3.4microg/ml post-48-h treatment, its action mechanism via induction of apoptosis involved both extrinsic and intrinsic pathways. | |
| BCN4531 | Ailanthone |
| Ailanthone has anti-inflammatory, anti-HIV, anti-malarial, anti-allergic, antiulcer and antimicrobial activities; it also has potent antineoplastic activity against hepatocellular carcinoma (HCC), it can inhibit huh7 cancer cell growth via cell cycle arrest and apoptosis in vitro and in vivo. Ailanthone has significant pre-emergence herbicide activity , is directly correlated to Ailanthone concentration. | |
| BCN4537 | 3,4-Dihydroxybenzoic acid |
| 3,4-Dihydroxybenzoic acid shows significant nematicidal, antitumor, neuroprotective, antioxidant, and antimicrobial activities. 3,4-Dihydroxybenzoic acid has protection against adriamycin cytotoxicity and inhibition of DNA topoisomerase II activity; it also protects human keratinocytes against UVB-induced oxidative stress and apoptosis.3,4-Dihydroxybenzoic acid can prevent Abeta (25-35)-induced neuronal cell damage by interfering with the increase of [Ca(2+)](c), and then by inhibiting glutamate release, generation of ROS and caspase-3 activity. | |
