Products with Anticancer bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4650 | Paclitaxel |
| Paclitaxel is a potent anticancer medication which can promote microtubule (MT) assembly, inhibits MT depolymerization, and changes MT dynamics required for mitosis and cell proliferation. Paclitaxel can induce ototoxicity in rats. | |
| BCN4655 | Deoxyelephantopin |
| 1. Deoxyelephantopin has hepatoprotective activity. 2. Deoxyelephantopin has wound healing activity. 3. Deoxyelephantopin has anti-inflammatory activity. 4. Deoxyelephantopin has antitumor activity, by inhibiting metastatic, inducing apoptosis, modulating oxidative stress , STAT3/p53/p21 signaling, MAPK pathway, PI3k/Akt/mTOR pathway, caspase cascades, and ROS . | |
| BCN4661 | Schleicheol 1 |
| 1. Schleicheol 1 has antitumor activity, it possesses inhibitory activity against SGC-7901 cell line. | |
| BCN4685 | Scabertopin |
| 1. Scabertopin exhibits significant antitumor effect in vitro in a concentration-dependent manner. | |
| BCN4725 | Sulfuretin |
| 1. Sulfuretin may have therapeutic value in preventing or delaying the progression of rheumatoid arthritis. 2. Sulfuretin has therapeutical effect on leukemia, due to its potent apoptotic activity through the extrinsic pathway driven by a Fas-mediated caspase-8-dependent pathway. 3. Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 through the Nrf2/ARE and JNK/ERK signaling pathways. 4. Sulfuretin may have a potential role for neuroprotection, possibly through inhibition of phosphorylation of MAPK, PI3K/Akt, and GSK-3β, which leads to mitochondrial protection, NF-κB modulations and subsequent suppression of apoptosis via ROS-dependent pathwaysand, may be used as a therapeutic agent for PD. | |
