Products with Anticancer bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4786 | Altholactone |
| 1. Altholactone can inhibit the growth of various types of cancer cells through inducing apoptosis via oxidative stress, including bladder cancer, colon carcinoma cells. 2. Altholactone may be a potential antimicrobial agent, particularly in ciprofloxacin-refractory S. aureus and E. faecalis infections. | |
| BCN4804 | Deguelin |
| 1. Deguelin has anti-cancer activity, such as anti osteosarcoma, lung cancer; via inducing the apoptosis of cancer cells through a ROS driven Akt pathway, EPC suppression by FAK-integrin-ILK-dependent actin remodeling . 2. Deguelin possesses antitumor effect by targeting Akt in dual axis such as EGFR and IGF1R signaling pathways and suggests that it provides an applicable therapeutic strategy for HNSCC patients. 3. Deguelin is a potent in vitro inhibitor of the mutant form of NPM1, which provides the molecular basis for its anti-leukemia activities in NPM1 mutant acute myeloid leukemia cells. | |
| BCN4816 | Phaseollin |
| 1. Phaseollin and neorautenol may be responsible for the anticarcinogenic actions of the plant extract, may lead to new pharmacons to be used in cancer therapy. 2. 9-Aminoacridine and other DNA intercalators function as inducers of Phaseollin and phenylalanine ammonia lyase synthesis by reacting with the DNA template. 3. The red kidney bean phytoalexins kievitone and phaseollin possess both estrogenic and antiestrogenic activities. | |
| BCN4819 | Maltol |
| Maltol is a naturally occurring organic compound that is flavour enhancer and flavouring agent. Maltol has neuroprotective effects against hypoxia-induced neuroretinal cell damage in R28 cells, and it has potential as a new neuroprotective therapeutic agent for oxidative stress-related ocular diseases, including glaucoma.Maltol exhibits hepatoprotective effect on alcohol-induced liver oxidative injury, may due to its potent antioxidant properties. | |
| BCN4853 | Enniatin B1 |
| 1. Enniatin B1 has intestinal toxicity. 2. Enniatins A, A(1), B, B(1) have antifungal effects. 3. Enniatins A1, B and B1 induce apoptotic cell death in H4IIE hepatoma cells accompanied by inhibition of ERK phosphorylation. | |
