Products with Anticancer bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3706 | 14-Deoxyandrographolide |
| 1. 14-Deoxyandrographolide desensitizes hepatocytes to TNF-alpha-mediated apoptosis through the release of TNFRSF1A. 2. 14-Deoxyandrographolide has hepatoprotective activity, mediates activation of adenylate cyclase-cAMP signaling leading to up-regulation of cNOS, may provide a promising approach in the prevention of liver diseases during chronic alcoholism. | |
| BCN3716 | Ginsenoside Rs3 |
| 1. Ginsenoside Rs3 induce apoptosis, is related to the elevations of p53 and p21WAF1 in the cells. | |
| BCN3720 | Gama-Tocotrienol |
| 1. Gamma-Tocotrienol has antioxidant activity, it as a hypocholesterolemic and antioxidant agent in rats fed atherogenic diets. 2. Gamma-Tocotrienol can induce the apoptosis on human gastric cancer SGC-7901 cells via mitochondria-dependent apoptosis pathway, it may as a potential, new chemopreventive agent for human gastric cancer. 3. Gamma-Tocotrienol is a novel blocker of the STAT3 activation pathway, with a potential role in future therapies for HCC and other cancers. | |
| BCN3721 | Ginsenoside Rk2 |
| Ginsenoside Rk1 has anti-tumor, and anti-platelet aggregation activities. Ginsenoside Rk1 can strongly inhibit permeability induced by VEGF, advance glycation end-product, thrombin, or histamine in human retinal endothelial cells, it reduces the vessel leakiness of retina in a diabetic mouse model; this anti-permeability activity of Rk1 is correlated with enhanced stability and positioning of tight junction proteins at the boundary between cells; Rk1 induces phosphorylation of myosin light chain and cortactin, which are critical regulators for the formation of the cortical actin ring structure and endothelial barrier. | |
| BCN3736 | 3-Deoxysappanchalcone |
| 1. 3-Deoxysappanchalcone is an effective HO-1 inducer at the translational level. 2. 3-Deoxysappanchalcone has anti-inflammatory effects, is a valuable compound for modulating inflammatory conditions. 3. 3-Deoxysappanchalcone has anti-influenza virus activity, the mechanism involved anti-apoptosis and anti-inflammation activities in vitro. 4. 3-Deoxysappanchalcone has inhibitory activity on MMP-9 expression and production in TNF-α-treated cells, is mediated by the suppression of AP-1 and NF-κB activation. | |
