Products with Antidepressant bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2719 | 3,6'-Disinapoyl sucrose |
| 3,6'-Disinapoyl sucrose has neuroprotective effect and antidepressive activity in rats, at least in part, by increasing expression of cyclic AMP response element (CRE)-binding protein (CREB) and its downstream target protein, brain-derived neurotrophic factor (BDNF). 3,6'-Disinapoyl sucrose protect neuron cells from glutamate-induced excitotoxicity include the downregulation of proapoptotic gene Bax and the upregulation of antiapoptotic gene Bcl-2. | |
| BCN2785 | Sibiricose A5 |
| Sibiricose A5 is a lactate dehydrogenase inhibitor, it displays antidepressant-like, and antioxidant actions. Sibiricose A5 can protect PC12 cells damage induced by P. tenuifolia. | |
| BCN2786 | Sibiricose A6 |
| Sibiricose A6 displays antidepressant-like action, it may prevent or relieve depression; it also shows potent antioxidant activity. | |
| BCN3830 | Incensole acetate |
| Incensole acetate is a novel anti-inflammatory compound that inhibits NF-κB activation. Incensole acetate has protective effects on cerebral ischemic injury, it can reduce depressive-like behavior and modulate hippocampal BDNF and CRF expression of submissive animals. | |
| BCN4090 | Uridine |
| Uridine has antidepressant-like effects, and it has protective effects against drug-induced fatty liver. Uridine can increase the rate of potassium transport in mitochondria isolated from liver of low resistant rats, and inhibitors of the channel prevent the channel activating effect of Uridine. Uridine has inhibition of p53-dependent intestinal apoptosis initiated by 5-fluorouracil. | |
