Products with Antifungal bioactivity

Cat.No. Product Name
BCN3046 Chamaejasmenin D
1. Chamaejasmenin D, isochamaejasmenin B and chamaejasmenin A demonstrates potent antimitotic and antifungal activity with minimum inhibitory concentration (MIC) values of 6.25, 6.25, and 3.12 microg/ml, respectively.
BCN3065 Zeylasteral
Zeylasteral and demethylZeylasteral are 6-oxophenolic triterpenoids isolated from the root of Maytenus blepharodes. Zeylasteral and demethylZeylasteral have antimicrobial activity against Gram-positive bacteria and the yeast Candida albicans.
BCN3155 Ferruginol
1. Ferruginol has anti-plasmodial, leishmanicidal, anti-ulcerogenic activities. 2. Ferruginol has cardioprotective, anti-oxidative and anti-inflammatory activities. 3. Ferruginol has anticancer activity, can induce apoptosis in non-small cell lung cancer (NSCLC) cells. 4. Ferruginol has antimicrobial and antifungal activities against wood-rot fungi (basidiomycetes), can cause cellular dysfunction and damage, lead to growth inhibition and autophagic cell death of fungi.
BCN3218 6,7-Dehydroferruginol
1. 6,7-Dehydroferruginol has potent activity against F. palustris . 2. 6,7-Dehydroferruginol and sugiol are weakly active against Heterosigma akashiwo.
BCN3254 (-)-Pinoresinol
1. Pinoresinol (PIN)can ameliorate CCl4-induced acute liver injury, and this protection is likely due to anti-oxidative activity and down-regulation of inflammatory mediators through inhibition of NF-kappaB and AP-1. 2. (+)-Pinoresinol possesses fungicidal activities and therapeutic potential as an antifungal agent for the treatment of fungal infectious diseases in humans. 3. Pinoresinol is the precursor of other dietary lignans that are present in whole-grain cereals, legumes, fruits, and other vegetables, PIN can cause an upregulation of the CDK inhibitor p21(WAF1/Cip1) both at mRNA and protein levels, suggests that this could be a mechanism by which PIN reduces proliferation and induces differentiation on HL60 cells.

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