ZeylasteralCAS# 87064-16-2 |
Quality Control & MSDS
3D structure
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Number of papers citing our products
| Cas No. | 87064-16-2 | SDF | Download SDF |
| PubChem ID | 11591321 | Appearance | Powder |
| Formula | C30H38O6 | M.Wt | 494.6 |
| Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | methyl (2R,4aS,6aR,6aS,14aS,14bR)-9-formyl-10,11-dihydroxy-2,4a,6a,6a,14a-pentamethyl-8-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylate | ||
| SMILES | CC12CCC(CC1C3(CCC4(C5=CC(=C(C(=C5C(=O)C=C4C3(CC2)C)C=O)O)O)C)C)(C)C(=O)OC | ||
| Standard InChIKey | HFOZJSCLBUTFCX-NLVUKCNFSA-N | ||
| Standard InChI | InChI=1S/C30H38O6/c1-26-7-8-27(2,25(35)36-6)15-22(26)30(5)12-10-28(3)18-13-20(33)24(34)17(16-31)23(18)19(32)14-21(28)29(30,4)11-9-26/h13-14,16,22,33-34H,7-12,15H2,1-6H3/t22-,26-,27-,28+,29-,30+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Zeylasteral and demethylZeylasteral are 6-oxophenolic triterpenoids isolated from the root of Maytenus blepharodes. Zeylasteral and demethylZeylasteral have antimicrobial activity against Gram-positive bacteria and the yeast Candida albicans. |
| Targets | Antifection |
| In vitro | Antimicrobial activity of 6-oxophenolic triterpenoids. Mode of action against Bacillus subtilis.[Pubmed: 15856406]Planta Med. 2005 Apr;71(4):313-9.Zeylasteral and demethylZeylasteral are 6-oxophenolic triterpenoids isolated from the root of Maytenus blepharodes, which have antimicrobial activity against Gram-positive bacteria and the yeast Candida albicans.
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Zeylasteral Dilution Calculator
Zeylasteral Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.0218 mL | 10.1092 mL | 20.2184 mL | 40.4367 mL | 50.5459 mL |
| 5 mM | 0.4044 mL | 2.0218 mL | 4.0437 mL | 8.0873 mL | 10.1092 mL |
| 10 mM | 0.2022 mL | 1.0109 mL | 2.0218 mL | 4.0437 mL | 5.0546 mL |
| 50 mM | 0.0404 mL | 0.2022 mL | 0.4044 mL | 0.8087 mL | 1.0109 mL |
| 100 mM | 0.0202 mL | 0.1011 mL | 0.2022 mL | 0.4044 mL | 0.5055 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Antimicrobial activity of 6-oxophenolic triterpenoids. Mode of action against Bacillus subtilis.[Pubmed:15856406]
Planta Med. 2005 Apr;71(4):313-9.
Zeylasteral and demethylZeylasteral are 6-oxophenolic triterpenoids isolated from the root of Maytenus blepharodes, which have antimicrobial activity against Gram-positive bacteria and the yeast Candida albicans. The time-kill curves for Zeylasteral and demethylZeylasteral at concentrations twice their MICs, against Bacillus subtilis showed that the colony forming units were reduced in 3-log10 and > 4-log10 respectively. This reduction was dependent on inoculum size and the growth phase of cells, and was greater when the compounds were incorporated in the exponential phase, indicating a bacteriolytic effect. Treatment with both agents, particularly with Zeylasteral (20 microg/mL) caused a reduction of optical density at 550 nm. With regard to the synthesis of DNA, RNA, protein and cell wall, the compounds exhibited the fastest inhibition against cell wall synthesis. Thus, the predisposition to lysis, the morphological changes seen by microscopy, and the complete inhibition in the incorporation the N-acetyl-d-[1 - 14C]glucosamine, suggest that the phenolic compounds compromise the cell wall synthesis and/or cytoplasmic membrane.
