Products with Antihypertensive bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2686 | Cineole |
| Cineole has antihypertensive,and anti-inflammatory effects, it regulates nitric oxide and oxidative stress in rats chronically exposed to nicotine. Cineole can attenuate cerulein-induced AP via an anti-inflammatory mechanism and by combating oxidative stress, may can treat neurodegenerative disease. | |
| BCN2709 | Isorhamnetin 3-glucuronide |
| 1. Isorhamnetin - 3 -O -glucuronide exerts anti-inflammatory activity by increasing heme oxygenase-1 (HO-1) expression and by suppressing Jun N-terminal kinase (JNK) and p38 signaling pathways in LPS-challenged RAW264.7 macrophage cells. 2. Isorhamnetin-3-glucuronide(1 mg/kg i.v.) can progressively reduce mean blood pressure (MBP), measured in conscious spontaneously hypertensive rats (SHR). 3. Isorhamnetin 3-glucuronide can inhibit vascular cell adhesion molecule-1 (VCAM-1) cell surface expression at 2 micromol/L, indicates that it can inhibit the expression of key molecules involved in monocyte recruitment during the early stages of atherosclerosis at physiological concentrations. | |
| BCN2758 | Hirsutine |
| Hirsutine has anticancer, cardioprotective, anti‑hypertensive and anti-arrhythmic activities, it also has vasodilatation activity, the mechanism is related to blockade of Ca2+ influx through L-type Ca2+ channels and inhibition of intracellular Ca2+ release may have no relationship with K+ channels. Hirsutine reduces the production of various neurotoxic factors in activated microglial cells and possesses neuroprotective activity in a model of inflammation-induced neurotoxicity. | |
| BCN2794 | Pseudoginsenoside RT1 |
| 1. Pseudoginsenoside RT1 can cause a decrease in blood pressure, an increase in heart rate and an increase in spontaneous contractility of the uterus. | |
| BCN2965 | Veratramine |
| Veratramine exhibits cytotoxic activity against human tumor cell lines A549, PANC-1, SW1990 and NCI-H249. Veratramine shows hypotensive effect, the effect is directly positively correlated with the dosage. | |
