Products with Antihypertensive bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3296 | Dicentrine |
| 1. Dicentrine has antinociception in different models of chemical pain. 2. Dicentrine induces DNA lesions to arrest cell cycle. 3. Dicentrine, a selective α(1)-adrenoceptor antagonist with potent antiarrhythmic and antihypertensive activities. 4. Callus and cell suspension cultures of S. venosa can produce high levels of Dicentrine as an alternative source of plant materials. | |
| BCN3466 | Isorhyncophylline |
| Isorhyncophylline and rhyncophylline can directly inhibit the contractile responses induced by several agonists in small blood vessels of rat, they also can inhibit the hypertensive effect of angiotensin Ⅱ. | |
| BCN3669 | Tilianin |
| 1. Tilianin has anti-inflammatory activity. 2. Tilianin has antiatherogenic activity. 3. Tilianin inhibits the tumor necrotic factor-K (TNF-K)-induced expression of VCAM-1 by 74% and reduces TNF-K-induced activation of nuclear factor-UB in cultured human umbilical vein endothelial cells (HUVECs). 4. Tilianin has antihypertensive and vasorelaxant activities, mediates relaxation and antihypertension mainly by an endothelium-dependent manner, probably due to NO release, and also through an endothelium-independent pathway by opening K+ channels. | |
| BCN3835 | Kukoamine A |
| 1. Kukoamine A shows hypotensive activity. | |
| BCN4074 | Methyleugenol |
| Methyleugenol (ME) is a natural constituent of the essential oils of a number of plants widely used in foodstuffs as flavouring agents, in view of the carcinogenic potential of ME, the need to check its presence in food products with effective analytical methods. ME has elaxant and antispasmodic actions on guinea-pig isolated ileum, it also has antinociceptive, anti-inflammatory, and insecticidal properties.ME can inhibit the production of nitric oxide and decreased the protein expression of inducible nitric oxide synthase, it down-regulates the production of pro-inflammatory cytokines in the ischemic brain as well as in immunostimulated mixed glial cells. | |
