Products with Antileukaemic bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3816 | Gardenin B |
| Gardenin B exhibits superior antiproliferative activity against lung, breast, colon, hepatic and leukaemia cell lines as well as in keratinocytes .Gardenin B-induced cell death in human leukemia cells involves multiple caspases but is independent of the generation of reactive oxygen species. Gardenin B can strongly inhibit biochemical production of nitric oxide (IC50=10.59±0.4 ug/mL). | |
| BCN3876 | Perillyl alcohol |
| Perillyl alcohol has potential chemopreventive, and antileukemia activities, it can suppress antigen-induced immune responses in the lung, it could be a novel preventive or therapeutic option for immunologic lung disorders such as asthma with minimal side effects. Perillyl alcohol can suppress antigen-induced immune responses in the lung, it could be a novel preventive or therapeutic option for immunologic lung disorders such as asthma with minimal side effects. | |
| BCN4101 | Tagitinin F |
| 1. Tagitinin F shows in vitro leishmanicidal activities against Leishmania braziliensis promastigotes and amastigotes. 2. Tagitinin F possesses antileukemic activity. | |
| BCN4201 | Benzoic acid |
| Benzoic acid is a colorless crystalline solid and a simple aromatic carboxylic acid, used as a food preservative. Benzoic acid can improve feed efficiency and diarrhoea, and improve gut microfloral composition. | |
| BCN4318 | Camptothecin |
| Camptothecin is a specific inhibitor of DNA topoisomerase I (Topo I) with IC50 of 0.68 μM; it is a novel alkaloidal leukemia and tumor inhibitor, is a strong inhibitor of nucleic acid synthesis in mammalian cells and a potent inducer of strand breaks in chromosomal DNA. Camptothecin and its analogs reduce amyloid-β production and amyloid-β42-induced IL-1β production. | |
