Products with Antioxidants Bioactivity

Explore BioCrick products associated with Antioxidants biological activity, including catalog numbers, product names and available bioactivity information.

Cat. No.	Product Name
BCN3261	Chebulanin
1. Chebulanin is a topoisomerase I inhibitor. 2. Chebulanin inhibits the calcineurin pathway in C. neoformans. 3. Chebulanin exhibits potent antifungal activity against various human pathogenic fungi with minimum inhibitory concentrations ranging from 0.25 to over 64 μg/ml. 4. Chebulanin suppresses the expression of inflammatory mediators and prevents cartilage destruction and bone erosion in mice, therefore, chebulanin is a strong therapeutic alternative for the treatment of rheumatism arthritis. 5. Chebulanin shows strong radical scavenging activity, good potency to chelate Fe2⁺ and good inhibition ability of lipid peroxidation. 6. Chebulanin has apparent capacities of inhibiting the survival of MCF-7 human cancer cell line.
BCN3262	Chebulagic acid
Chebulagic acid is a potent DNA topoisomerase inhibitor, and is also COX-2 and 5-LOX dual inhibitor. Chebulagic acid may be of value as broad-spectrum antivirals for limiting emerging/ recurring viruses known to engage host cell glycosaminoglycans for entry. Chebulagic acid can be used to control blood glucose and manage type 2 diabetes, although clinical trials are needed.
BCN3263	Chebulinic acid
Chebulinic acid is a potent natural inhibitor of M. tuberculosis DNA gyrase, also can inhibit SMAD-3 phosphorylation, inhibit H+ K+-ATPase activity; it also is a natural inhibitor of vascular endothelial growth factor-A mediated angiogenesis. Chebulinic acid has hypotensive, antioxidant, anti-HIV, and anti-ulcer activities. Chebulinic acid has inhibitory effect on erythroid differentiation likely through changing transcriptional activation of differentiation relative genes, it or other tannins might influence the efficiency of some anti-tumor drugs-induced differentiation or the hematopoiesis processes.
BCN3265	1-Dehydro-6-gingerdione
1. 1-Dehydro-6-gingerdione is 5-HT1A receptor partial agonists. 2. 1-Dehydro-6-gingerdione has antioxidant and anti-inflammatory activities. 3. 1-Dehydro-6-gingerdione significantly suppresses the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) proteins in a concentration-dependent fashion.
BCN3267	10-Shogaol
1. 10-Shogaol, as an antioxidant for human skin cell growth and a migration enhancer with potential to be a novel wound repair agent. 2. 8- and 10-Shogaol have similar metabolic profiles to [6]-shogaol and exhibit similar toxicity toward human colon cancer cells.

Antioxidants Bioactivity Products