Products with
Antiviral bioactivity
Cat.No.
|
Product Name
|
BCN2894 |
Bruceine D
|
1. Bruceine D from Brucea javanica, may have the potential to be used as a natural viricide, or a lead compound for new viricides.
2. Bruceine D inhibits the growth of three pancreatic cancer cell lines, i.e., PANC-1, SW1990 and CAPAN-1; induces cytotoxicity in Capan-2 cells via the induction of cellular apoptosis involving the mitochondrial pathway. |
BCN2919 |
Isosinensetin
|
Isosinensetin shows antioxidant and HIV-1 protease inhibiting activities. |
BCN2957 |
Cephalotaxine
|
Cephalotaxine is an antiviral as well as antitumor agent. It is useless for the treatment of infection by flaviviruses, but potentially useful in combined therapy against hepatitis B. |
BCN2961 |
Ingenol 3-Angelate
|
1. Ingenol-3-angelate suppresses HIV infection of primary CD4+ T cells through down-modulation of cell surface expression of HIV co-receptors.
2. Ingenol 3-angelate activates a broad range of PKC isoforms and induces apoptosis in acute myeloid leukemia cells by activating the PKC isoform PKCdelta.
3. Ingenol-3-angelate shows anticancer activity, and P-gp-mediated absorptive transport, dermal penetration, and vascular damage contribute to the anticancer activity of ingenol-3-angelate in vivo.
4. Ingenol-3-angelate emerges as a unique local chemotherapeutic immunostimulatory debulking agent that could be used in conjunction with immunotherapies to promote regression of metastases. |
BCN2976 |
Tiglicacid
|
Tiglic acid shows antiviral activity toward herpes simplex virus type 1. |