Products with Antiviral bioactivity

Cat.No. Product Name
BCN2894 Bruceine D
1. Bruceine D from Brucea javanica, may have the potential to be used as a natural viricide, or a lead compound for new viricides. 2. Bruceine D inhibits the growth of three pancreatic cancer cell lines, i.e., PANC-1, SW1990 and CAPAN-1; induces cytotoxicity in Capan-2 cells via the induction of cellular apoptosis involving the mitochondrial pathway.
BCN2919 Isosinensetin
Isosinensetin shows antioxidant and HIV-1 protease inhibiting activities.
BCN2957 Cephalotaxine
Cephalotaxine is an antiviral as well as antitumor agent. It is useless for the treatment of infection by flaviviruses, but potentially useful in combined therapy against hepatitis B.
BCN2961 Ingenol 3-Angelate
1. Ingenol-3-angelate suppresses HIV infection of primary CD4+ T cells through down-modulation of cell surface expression of HIV co-receptors. 2. Ingenol 3-angelate activates a broad range of PKC isoforms and induces apoptosis in acute myeloid leukemia cells by activating the PKC isoform PKCdelta. 3. Ingenol-3-angelate shows anticancer activity, and P-gp-mediated absorptive transport, dermal penetration, and vascular damage contribute to the anticancer activity of ingenol-3-angelate in vivo. 4. Ingenol-3-angelate emerges as a unique local chemotherapeutic immunostimulatory debulking agent that could be used in conjunction with immunotherapies to promote regression of metastases.
BCN2976 Tiglicacid
Tiglic acid shows antiviral activity toward herpes simplex virus type 1.

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