Tiglicacid

CAS# 80-59-1

Tiglicacid

2D Structure

Catalog No. BCN2976----Order now to get a substantial discount!

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Tiglicacid: 5mg $23 In Stock
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3D structure

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Tiglicacid

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Chemical Properties of Tiglicacid

Cas No. 80-59-1 SDF Download SDF
PubChem ID 125468 Appearance Oil
Formula C5H8O2 M.Wt 100.1
Type of Compound Miscellaneous Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (E)-2-methylbut-2-enoic acid
SMILES CC=C(C)C(=O)O
Standard InChIKey UIERETOOQGIECD-ONEGZZNKSA-N
Standard InChI InChI=1S/C5H8O2/c1-3-4(2)5(6)7/h3H,1-2H3,(H,6,7)/b4-3+
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Tiglicacid

The roots of Angelica sinensis

Biological Activity of Tiglicacid

DescriptionTiglic acid shows antiviral activity toward herpes simplex virus type 1.
TargetsHSV
In vitro

Calysolins X-XIII, resin glycosides from Calystegia soldanella, and their antiviral activity toward herpes simplex virus.[Pubmed: 25087638]

Chem Pharm Bull (Tokyo). 2014;62(8):839-44.

Four new resin glycosides having macrolactone structures (jalapins), named calysolins X (1)-XIII (4), were isolated from the leaves, stems, and roots of Calystegia soldanella ROEM. et SCHULT. (Convolvulaceae).
METHODS AND RESULTS:
Their structures were determined on the basis of spectroscopic data as well as chemical evidence. The sugar moieties of 1-4 were partially acylated by some organic acids, including Tiglic acid, 2S-methylbutyric acid, and 2S,3S-nilic acid. Additionally, the antiviral activity of 1-4 toward herpes simplex virus type 1 was evaluated.
CONCLUSIONS:
All the compounds showed antiviral activity.

Tiglicacid Dilution Calculator

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Tiglicacid Molarity Calculator

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Preparing Stock Solutions of Tiglicacid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 9.99 mL 49.95 mL 99.9001 mL 199.8002 mL 249.7502 mL
5 mM 1.998 mL 9.99 mL 19.98 mL 39.96 mL 49.95 mL
10 mM 0.999 mL 4.995 mL 9.99 mL 19.98 mL 24.975 mL
50 mM 0.1998 mL 0.999 mL 1.998 mL 3.996 mL 4.995 mL
100 mM 0.0999 mL 0.4995 mL 0.999 mL 1.998 mL 2.4975 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Tiglicacid

Calysolins X-XIII, resin glycosides from Calystegia soldanella, and their antiviral activity toward herpes simplex virus.[Pubmed:25087638]

Chem Pharm Bull (Tokyo). 2014;62(8):839-44.

Four new resin glycosides having macrolactone structures (jalapins), named calysolins X (1)-XIII (4), were isolated from the leaves, stems, and roots of Calystegia soldanella ROEM. et SCHULT. (Convolvulaceae). Their structures were determined on the basis of spectroscopic data as well as chemical evidence. The sugar moieties of 1-4 were partially acylated by some organic acids, including tiglic acid, 2S-methylbutyric acid, and 2S,3S-nilic acid. Additionally, the antiviral activity of 1-4 toward herpes simplex virus type 1 was evaluated. All the compounds showed antiviral activity.

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