Home >> Research Area >>Natural Products>>Miscellaneous>> Soybean phospholipid

Soybean phospholipid

CAS# 8002-43-5

Soybean phospholipid

Catalog No. BCN3888----Order now to get a substantial discount!

Product Name & Size Price Stock
Soybean phospholipid: 5mg Please Inquire In Stock
Soybean phospholipid: 10mg Please Inquire In Stock
Soybean phospholipid: 20mg Please Inquire Please Inquire
Soybean phospholipid: 50mg Please Inquire Please Inquire
Soybean phospholipid: 100mg Please Inquire Please Inquire
Soybean phospholipid: 200mg Please Inquire Please Inquire
Soybean phospholipid: 500mg Please Inquire Please Inquire
Soybean phospholipid: 1000mg Please Inquire Please Inquire

Quality Control of Soybean phospholipid

Number of papers citing our products

Chemical structure

Soybean phospholipid

3D structure

Chemical Properties of Soybean phospholipid

Cas No. 8002-43-5 SDF Download SDF
PubChem ID 5287971 Appearance Powder
Formula C42H80NO8P M.Wt 758.1
Type of Compound Miscellaneous Storage Desiccate at -20°C
Solubility DMSO : 5 mg/mL (6.60 mM; Need ultrasonic)
H2O : 3.33 mg/mL (4.39 mM; Need ultrasonic)
Chemical Name [(2R)-3-hexadecanoyloxy-2-[(9Z,12Z)-octadeca-9,12-dienoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
SMILES CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCC=CCCCCC
Standard InChIKey JLPULHDHAOZNQI-ZTIMHPMXSA-N
Standard InChI InChI=1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Soybean phospholipid

The seeds of Glycine max

Biological Activity of Soybean phospholipid

DescriptionSoybean phospholipid has a growth-promoting effect and it is suitable as a lipid and phospholipid source in microdiets for P. fulvidraco larvae feed.Soybean phospholipid and safflower phospholipid can suppress the elevation of plasma and liver cholesterol and that this effect may be brought about by inhibiting the absorption of cholesterol in the small intestine.
In vivo

Effect of soybean phospholipid supplementation in formulated microdiets and live food on foregut and liver histological changes of Pelteobagrus fulvidraco larvae[Reference: WebLink]

Aquaculture, 2008, 278(1-4):119-27.


METHODS AND RESULTS:
The effect of supplementation of Soybean phospholipid (PL) to Pelteobagrus fulvidraco larvae diets on growth and histological changes in intestine and liver were investigated. P. fulvidraco larvae were fed from day 6 to 21 posthatch with four diets containing the same basal diet, coated with different lipid fractions (6% diet). The lipid fractions consisted of increasing levels of soybean PL (0, 2, 4 or 6% of diet) and decreasing levels of mixed oil (fish oil:soybean oil, 2:1). A group of larvae was fed rotifers as a control. The body weight and total length of larvae increased as a result of PL supplementation. Larvae fed diet supplemented with 6% PL exhibited the best growth performance and similar to those fed rotifers. Larvae fed 6% PL and larvae fed rotifers had normal appearance of enterocytes and liver. The addition of PL to the diet caused a reduction in the degree of lipid accumulation and an increased number of goblet cells in the enterocytes of the anterior intestine. The degree of lipid accumulation in the anterior intestine and in the liver on day 21 was lower than that on day 14, which indicated that the ability of PL synthesis was enhanced as the fish aged.
CONCLUSIONS:
These results confirm that PL has a growth-promoting effect and indicate that soybean PL is suitable as a lipid and PL source in microdiets for P. fulvidraco larvae feed.

Soybean phospholipid Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Soybean phospholipid Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Soybean phospholipid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.3191 mL 6.5954 mL 13.1909 mL 26.3817 mL 32.9772 mL
5 mM 0.2638 mL 1.3191 mL 2.6382 mL 5.2763 mL 6.5954 mL
10 mM 0.1319 mL 0.6595 mL 1.3191 mL 2.6382 mL 3.2977 mL
50 mM 0.0264 mL 0.1319 mL 0.2638 mL 0.5276 mL 0.6595 mL
100 mM 0.0132 mL 0.066 mL 0.1319 mL 0.2638 mL 0.3298 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University

Background on Soybean phospholipid

Lecithin is regarded as a safe, conventional phospholipid source. Phospholipids are reported to alter the fatty acid composition and microstructure of the membranes in animal cells.

In Vitro:After culturing in MRS broth with 0.2 to 1.0% soy Lecithin, the survival rate of harvested cells increases significantly (P<0.05) in the 0.3% bile challenge compare with the no added soy Lecithin group. The cells incubated with 0.6% soy Lecithin are able to grow in an MRS broth with a higher bile salt content. The cell surface hydrophobicity is enhanced and the membrane integrity in the bile challenge increases after culturing with soy Lecithin. A shift in the fatty acid composition is also observed, illustrating the cell membrane changes in the soy Lecithin culture[1].

References:
[1]. Hu B, et al. Enhancement of bile resistance in Lactobacillus plantarum strains by soy lecithin. Lett Appl Microbiol. 2015 Jul;61(1):13-9.

Featured Products
New Products
 

References on Soybean phospholipid

Codelivery of Adriamycin and P-gp Inhibitor Quercetin Using PEGylated Liposomes to Overcome Cancer Drug Resistance.[Pubmed:30610857]

J Pharm Sci. 2019 Jan 2. pii: S0022-3549(18)30815-3.

Transmembrane protein P-gp's overexpression at the drug-resistant cell membrane is the most important characteristic of multidrug resistance (MDR). Quercetin (QUE) can effectively suppress the function of P-gp to reverse MDR. This study uses QUE as the P-gp inhibitor andfilm-ultrasound technique with ammonium sulfate transmembrane gradient method to prepare long-circulating liposomes simultaneously encapsulating QUE and Adriamycin (doxorubicin) (AMD/DOX). The optimal conditions for the preparation of AMD_QUE_long-circulating liposomes (SLs) are as follows: hydrogenated Soybean phospholipids (HSPC):cholesterol:DSPE-PEG 2000 = 73.07:24.36:2.57 mol/mol, QUE:HSPC = 1:20 mol/mol, AMD:HSPC = 1:7.9 w/w (NH4)2SO4 0.15 mol/L, drug loaded (AMD) at 55 degrees C for 25 min). The average encapsulation efficiency of AMD and QUE was 97.49% and 95.50%, respectively. The average particle size is 85 nm (n = 3), and the average zeta potential is -14.9 mV. First, the pharmacokinetic study proved that codelivery liposomes enveloping QUE and AMD (AMD_QUE_SL) can obviously increase the blood concentration of AMD (Cmax: 140.50 +/- 32.37 mug/mL) and extend the half-life period of AMD in plasma (t1/2:14.02 +/- 1.54 h). Second, AMD_QUE_SL can obviously enhance the cell toxicity to AMD-resistant cell strains (HL-6/ADR and MCF-7/ADR), and the reverse effects on the resistance of HL-6/ADR and MCF-7/ADR is increased to 4.81-fold and 3.21-fold, respectively. Third, according to the in vivo pharmacodynamic study, the relative tumor volume and relative tumor growth of the AMD_QUE_SL group were the lowest. The inhibition rate of tumor growth of this group was the highest. It can be concluded that AMD_QUE_SL can effectively reverse MDR, lower cardiac toxicity of AMD in clinical treatment, and improve the clinical treatment effect of AMD.

Lecithin soybean phospholipid nano-transfersomes as potential carriers for transdermal delivery of the human growth hormone.[Pubmed:30506803]

J Cell Biochem. 2019 Jun;120(6):9023-9033.

Pharmaceutical molecules such as peptides and proteins are usually injected into the body. Numerous efforts have been made to find new noninvasive ways to administer these peptides. In this study, highly flexible vesicles (transfersomes [TFs]) were designed as a new modern transdermal drug delivery system for systemic drug administration through the skin, which had also been evaluated in vitro. In this study, two growth hormone-loaded TF formulations were prepared, using soybean lecithin and two different surfactants; F1 _sodium deoxycholate and F 2 _sodium lauryl sulfate. Thereafter, the amount of skin penetration by the two formulas was assessed using the Franz diffusion cell system. TF formulations were evaluated for size, zeta potential and in vitro skin penetration across the rat skin. Results indicated that vesicle formulations were stable for 4 weeks and their mean sizes were 241.33 +/- 17 and 171 +/- 12.12 nm in the F 1 and F 2 formulation, respectively. After application to rat skin, transport of the human growth hormone (hGH) released from the TF formulations was found to be higher than that of the hGH alone. Maximum amounts of transdermal hormone delivery were estimated to be 489.54 +/- 8.301 and 248.46 +/- 4.019 ng.cm-2 , for F 1 and F 2 , respectively. The results demonstrate the capability of the TF-containing growth hormone in transdermal delivery and superiority of the F 1 to F 2 TFs.

Description

Lecithin is regarded as a safe, conventional phospholipid source. Phospholipids are reported to alter the fatty acid composition and microstructure of the membranes in animal cells.

Keywords:

Soybean phospholipid,8002-43-5,Natural Products, buy Soybean phospholipid , Soybean phospholipid supplier , purchase Soybean phospholipid , Soybean phospholipid cost , Soybean phospholipid manufacturer , order Soybean phospholipid , high purity Soybean phospholipid

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: