Products with Cytoprotective bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2941 | 6'-O-Galloyl paeoniflorin |
| 1. Galloylpaeoniflorin, gallic acid, paeoniflorin, and paeonol are the main effective components of Moutan Cortex, Moutan Cortex exhibits good activity on acute lung injury. 2. Galloylpaeoniflorin exhibits anticomplement effects. 3. Galloylpaeoniflorin reveals a more pronounced radical scavenging effect than a-tocopherol. 4. Galloylpaeoniflorin can take part in improving blood circulation by inhibiting ether platelet aggregation and/or blood coagulation. | |
| BCN3389 | 8-Hydroxypinoresinol |
| 1. 8-hydroxypinoresinol has antioxidant activity. 2. 8-hydroxypinoresinol and phillygenin significantly reduce the cell injury by 3-morpholinosydnonimine (SIN-1), a ONOO− generator, may be useful for the therapeutic or preventive applications in treating ONOO−-related diseases. | |
| BCN4225 | Catalposide |
| 1. Catalposide possesses antioxidant, anti-apoptotic, anti-microbial, anti-tumoral, and anti-inflammatory properties. 2. Catalposide is a potent inducer of HO-1 and HO-1 induction is responsible for the catalposide-mediated cytoprotection against oxidative damage. 3. Catalposide is a natural agonistic ligand of peroxisome proliferator-activated receptor-α, is hypolipidemic by activation of PPARαvia a ligand-mediated mechanism that modulates the expression of in lipid metabolism genes in hepatocytes. 4. Catalposide can attenuate induction of intestinal epithelial proinflammatory gene expression and reduce the severity of trinitrobenzene sulfonic acid-induced colitis in mice, it may be an effective agent for the treatment of diseases characterized by mucosal inflammation. | |
| BCN4843 | Pterisolic acid B |
| 1. Pterisolic acid B (J19) is an effective Nrf2 activator. we have also identified a more potent natural product analogue J19-1, J19-1 shows significant cytoprotective effect against cisplatin-induced cytotoxicity in HKC cells. | |
| BCN5164 | Feretoside |
| Feretoside can increase the expression of heat shock factor 1 (HSF1) by a factor of 1.153 at 3 uM. | |
