Products with Cytoprotective bioactivity
| Cat.No. | Product Name |
|---|---|
| BCC8030 | L-Glutathione Reduced |
| Glutathione plays important roles in antioxidant defense, nutrient metabolism, and regulation of cellular events (including gene expression, DNA and protein synthesis, cell proliferation and apoptosis, signal transduction, cytokine production and immune response, and protein glutathionylation); glutathione deficiency contributes to oxidative stress, which plays a key role in aging and the pathogenesis of many diseases (including kwashiorkor, seizure, Alzheimer's disease, Parkinson's disease, liver disease, cystic fibrosis, sickle cell anemia, HIV, AIDS, cancer, heart attack, stroke, and diabetes). | |
| BCN1028 | Morin |
| Morin, a α-glucosidase inhibitor with an IC50 value of (4.48 ± 0.04) uM, it also exhibits inhibition in the generation of advanced glycation end products which was related to the long term complications of diabetes. Morin has anti-inflammatory and anti-oxidative effects by activating Nrf2 signal pathways and inhibiting NF-κB activation. it can be used to prevent bladder cancer, it prevents MMP-9 expression via the inhibition of transcription factors AP-1, Sp-1, and NF-κB. | |
| BCN1047 | Bilirubin |
| Bilirubin is a tetrapyrrole and a breakdown product of heme catabolism, it is a prominent endogenous antioxidant cytoprotectant and a natural inhibitor of vascular smooth muscle cell proliferation, which has neuroprotective and anti- atherosclerosis-related diseases effects. It can act as an effective agent to reduce mortality and counteract hypotension elicited by endotoxin through mechanisms involving a decreased NOS2 induction secondary to inhibition of NAD(P)H oxidase. | |
| BCN1237 | Fraxin |
| Fraxin possesses a variety of bioactivities such as anti-inflammatory, antioxidant, analgesic, antimicrobial, antiviral, immunomodulatory, anti-hyperuricemia and diuresis. Fraxin enhances urate excretion partly by inhibiting mURAT1 or mGLUT9 in kidney of hyperuricemic mice. | |
