Products with Hepatoprotective bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3208 | Ganoderenic acid A |
| 1. Ganoderenic acid A show inhibitory activity on human aldose reductase in vitro. 2. Ganoderenic acid A has a potent hepatoprotective effect against CCl4-induced liver injury. 3. Ganoderenic acid A has cytotoxic activity, their inhibitory activities against human HeLa cervical cancer cell lines. | |
| BCN3360 | Alisol F |
| 1. Alisol F suppresses iNOS induction. 2. Alisol F and 25-Anhydroalisol F show anti-inflammatory activities and liver protection through the inhibition of MAPK, STAT3, and NF-κB activation in vitro and in vivo. 3. Alisol F exhibits inhibitory effects on lipopolysaccharide-induced NO production in RAW 264.7 macrophage cells. 4. Alisol F exhibits inhibitory activity in vitro on hepatitis B virus (HBV) surface antigen (HBsAg) secretion of the Hep G2.2.15 cell line with the IC (50) value of 0.6 microM, and on HBV e antigen (HBeAg) secretion with the IC (50) value of 8.5 microM. | |
| BCN3361 | 25-Anhydroalisol F |
| 1. 25-Anhydroalisol F shows anti-inflammatory activities and liver protection through the inhibition of MAPK, STAT3, and NF-κB activation in vitro and in vivo. 3. 25-Anhydroalisol F exhibits inhibitory effects on lipopolysaccharide-induced NO production in RAW 264.7 macrophage cells. | |
| BCN3408 | Gentisic acid |
| Gentisic acid, an active metabolite of salicylic acid degradation, has a broad spectrum of biological activity, such as antibiotic, anti-inflammatory, antirheumatic and antioxidant properties; it also has antimutagenic/protective effects that may contribute to human health. Gentisic acid has protective effect against cyclophosphamide induced genotoxicity and hepatotoxicity in Swiss albino mice. | |
| BCN3412 | Astringin |
| 1. Astringinin is a potent antiarrhythmic agent with cardioprotective activity in ischemic and ischemic-reperfused rat heart, the beneficial effects of astringinin in the ischemic and ischemic-reperfused hearts may be correlated with its antioxidant activity and upregulation of NO production. 2. Astringinin can significantly attenuate proinflammatory responses and hepatic injury after trauma-hemorrhage, the salutary effects of astringinin administration on attenuation of hepatic injury following trauma-hemorrhage are likely due to reduction of pro-inflammatory mediator levels. | |
