Products with Hepatoprotective bioactivity

Cat.No. Product Name
BCN3424 Trimethylgallic acid
Trimethylgallic acid esters are potent antioxidants and inhibitor of cytokine production, can ameliorate chronic stress-induced various behavioral and biochemical alterations in mice, showing protective effects against chronic stress; they also exert hepatoprotective effects in CCl4-induced rats, specifically by modulating oxidative-nitrosative stress and inflammation.
BCN3432 Chikusetsusaponin IVa
Chikusetsusaponin IVa is a novel AMPK activator, can induce insulin secretion from βTC3 cells via GPR40 mediated calcium and PKC pathways, may be developed into a new potential for therapeutic agent used in T2DM patients.Chikusetsusaponin IVa exerts antithrombotic effects, including minor hemorrhagic events.
BCN3447 Kurarinol
1. Kurarinol is a potent inhibitor of sortase A, with an IC50 value of 107.7 ± 6.6 μM. 2. Kurarinol has extremely strong tyrosinase inhibitory activity, exerts varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis, is a candidate as skin-whitening agents.
BCN3453 1,3,5,6-Tetrahydroxyxanthone
1. 1,3,5,6-Tetrahydroxyxanthone can inhibit angiotensin-I-converting-enzyme activity in a dose-dependent manner. 2. 1,3,5,6-Tetrahydroxyxanthone shows moderate hepatoprotective activity with EC(50) values of 160.2 +/- 0.6 microM against tacrine-induced cytotoxicity in HepG2 cells.
BCN3517 1beta-Hydroxyeuscaphic acid
1.1beta-Hydroxyeuscaphic acid has significant hepatoprotective activity by lowering the leakage of intracellular enzymes, reducing the oxidation of proteins and decreasing the incidence of apoptosis.

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