Products with
Hepatoprotective bioactivity
Cat.No.
|
Product Name
|
BCN3522 |
Curcumenol
|
Curcumenol possesses a variety of health and medicinal values which includes neuroprotection, anti-inflammatory, anti-tumor and hepatoprotective activities. It inhibits NF-κB activation by suppressing the nuclear translocation of the NF-κB p65 subunit and blocking IκBα phosphorylation and degradation. |
BCN3529 |
Aerugidiol
|
1.Aerugidiol inhibits protein tyrosine phosphatase 1B (PTP1B). |
BCN3556 |
13-Hydroxygermacrone
|
1. 13-Hydroxygermacrone inhibits UVB-induced upregulation of the mRNA and protein expression levels of MMP-1, MMP-2, and MMP-3 in human keratinocytes (HaCaT).
2. 13-Hydroxygermacrone shows a protective effect against D-GalN/tumor necrosis factor-alpha-induced liver injury in mice at a dose of 50 mg/kg p.o.
3. 13-Hydroxygermacrone inhibits the increase in serum aspartate aminotransaminase and alanine aminotransaminase at a dose of 50 mg/kg p.o. |
BCN3560 |
Zedoarondiol
|
1. Zedoarondiol has anti-inflammatory activity, inhibits iNOS, COX-2, and pro-inflammatory cytokine expressions by suppressing the phosphorylations of IKK and MAPKs, and by subsequently inactivating the NF-kappaB pathway.
2. Zedoarondiol dose-dependently inhibits LPS-stimulated nitric oxide (NO), prostaglandin E(2) (PGE(2)), tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), and interleukin-1beta (IL-1beta) productions in RAW 264.7 macrophage and in mouse peritoneal macrophage cells. |
BCN3606 |
(-)-beta-Peltatin
|
1. (-)-beta-Peltatin has antimitotic, and antineoplastic activities. |