Products with Hepatotoxicity bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN1982 | Heliotrine |
| 1. The pyrrolizidine alkaloid Heliotrine interferes with reporter signals derived from GAL4-based nuclear receptor transactivation assays by a mechanism independent of luciferase enzyme inhibition. 2. Acute hepatitis induced by Heliotrine is accompanied by uncoupling of oxidative phosphorylation in liver mitochondria. | |
| BCN1998 | 7-Acetylintermedine |
| 1.7-Acetylintermedine, 7-acetyllycopsamine, and symlandine are pyrrolizidine alkaloids, isolated from comfrey, can produce hepatotoxicity in livestock and humans and carcinogenicity in experimental animals. | |
| BCN2000 | 7-Acetyllycopsamine |
| 1. 7-Acetyllycopsamine, 7-acetylintermedine, and symlandine are pyrrolizidine alkaloids, isolated from comfrey, can produce hepatotoxicity in livestock and humans and carcinogenicity in experimental animals. 2. 7-Acetyllycopsamine exhibits antibacterial effects with a MIC of 1.7 mg/ml in E. coli. | |
| BCN2001 | Lasiocarpine |
| 1. Lasiocarpine can produce liver damage. 2. Lasiocarpine has antimitotic action. 3. Lasiocarpine has hepatocarcinogenicity, the effect can be better explained by its strong selection (promotion) influence on initiated hepatocytes, rather than by its very weak initiating activity. | |
| BCN2009 | Otonecine |
| 1.Otonecine-type PA induces hepatotoxicity, the formation of an unstable pyrrolic ester plays a key role. | |
