Products with Inhibitors Bioactivity

Explore BioCrick products associated with Inhibitors biological activity, including catalog numbers, product names and available bioactivity information.

Cat. No.	Product Name
BCN6474	Songoramine
1. Songoramine(10 uM) demonstrates significant hERG K+ channel inhibition.
BCN6477	Marein
1. Marein shows neuroprotective effect on PC12 cell damage induced by methylglyoxal, which is due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway, indicates that marein may be a potent compound for preventing/counteracting diabetic encephalopathy. 2. Marein shows antioxidant activity. 3. Marein can improve insulin resistance induced by high glucose in HepG2 cells through CaMKK/AMPK/GLUT1 to promote glucose uptake, through IRS/Akt/GSK-3β to increase glycogen synthesis, and through Akt/FoxO1 to decrease gluconeogenesis. 4. Marein shows Histone deacetylase enzymes (HDACs) inhibitory activity and it also can inhibit TNFα-induced NF-κB activation.
BCN6479	Desoxyrhapontigenin
1. Desoxyrhapontigenin shows significant monoamine oxidase inhibitory activities with the IC50 value of 11.5 ± 1.1 uM. 2. Desoxyrhapontigenin up-regulates Nrf2-mediated heme oxygenase-1(HO-1) expression in macrophages and inflammatory lung injury, and HO-1 is an important anti-inflammatory, antioxidative and cytoprotective enzyme. 3. Desoxyrhapontigenin shows anti-inflammatory properties by the inhibition of iNOS and COX-2 expression via the down-regulation of the MAPK signaling pathways and the inhibition of NF-κB and Akt activation. 4. Desoxyrhapontigenin and desoxyrhaponticin have significant hypoglycemic and antioxidant effects.
BCN6480	Quercetagetin-7-O-glucoside
1. Quercetagetin-7-O-glucoside, quercetagetin, quercetagetin 3'-methyl ether 7-O-glucoside, patuletin, and patuletin 7-O-glucoside are "yellow flavonols", and it was shown that the flower colors of three yellow-flowered species are due to these compounds. 2. Quercetagetin-7-O-glucoside, a potent inhibitor of beta-glucuronidase and lysozyme release, shows anti-inflammatory activity, can significantly inhibit arachidonic acid release from membranes.
BCN6483	Epimedokoreanin B
1. Epimedokoreanin B can significantly inhibit the formation of both N (ε) -(carboxymethyl)lysine (CML) and N (ω) -(carboxymethyl)arginine (CMA), it may prevent clinical complications of diabetes by inhibiting advanced glycation end-products (AGEs). 2. Epimedokoreanin B shows scavenge the DPPH radical activity. 3. Epimedokoreanin B can inhibit the proliferation of MCF-7 and HepG2 in dose-dependant manner.

Inhibitors Bioactivity Products