Products with
Nematicidal bioactivity
Cat.No.
|
Product Name
|
BCN3131 |
Isoneochamaejasmine A
|
1. Isoneochamaejasmin A exhibits significantly nematicidal activities against both B. xylophilus and B. mucronatus. |
BCN3767 |
3-O-(2'E,4'Z-Decadienoyl)ingenol
|
1. 20-O-(2′E,4′Z-decadienoyl)ingenol, one toxic terpenoid from raw Gansui.
Kansuiphorin C and 3-O-(2′E,4′Z-decadienoyl)-ingenol exhibit significant anticomplement activity with respective 50% inhibitory concentration values of 44.1±3.8 and 89.5±5.5 uM.
2. 20-O-acetyl-[3-O-(2'E,4'Z)-decadienoyl]-ingenol and 3-O-(2'E,4'Z)-decadienoylingenol show the same antinematodal activity against the nematode, Bursaphelenchus xylophilus, at a minimum effective dose (MED) of 5 microg/cotton ball. |
BCN3780 |
2,5-dihydroxy-3-methoxy-Acetophenone
|
1. Acetophenones and chalcones may represent good leads in the discovery of new nematicidal compounds and may have potential use in crop management as active ingredients. |
BCN4296 |
8-Geranyloxypsoralen
|
8-Geranyloxypsoralen inhibits β-secretase (BACE1) activity in non-competitive manner, with the IC(50) values <25.0 uM, it can induce vasorelaxation on rat arterial tissues. 8-Geranyloxypsoralen possesses nematicidal activities, the median lethal concentrations (LC(50)) is 188.3 mg/ L against B. xylophilus and is 117.5 mg/L against P. redivivus. |
BCN4537 |
3,4-Dihydroxybenzoic acid
|
3,4-Dihydroxybenzoic acid shows significant nematicidal, antitumor, neuroprotective, antioxidant, and antimicrobial activities. 3,4-Dihydroxybenzoic acid has protection against adriamycin cytotoxicity and inhibition of DNA topoisomerase II activity; it also protects human keratinocytes against UVB-induced oxidative stress and apoptosis.3,4-Dihydroxybenzoic acid can prevent Abeta (25-35)-induced neuronal cell damage by interfering with the increase of [Ca(2+)](c), and then by inhibiting glutamate release, generation of ROS and caspase-3 activity. |