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2,5-dihydroxy-3-methoxy-Acetophenone

CAS# 90536-47-3

2,5-dihydroxy-3-methoxy-Acetophenone

2D Structure

Catalog No. BCN3780----Order now to get a substantial discount!

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2,5-dihydroxy-3-methoxy-Acetophenone: 5mg Please Inquire In Stock
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Quality Control of 2,5-dihydroxy-3-methoxy-Acetophenone

3D structure

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2,5-dihydroxy-3-methoxy-Acetophenone

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Chemical Properties of 2,5-dihydroxy-3-methoxy-Acetophenone

Cas No. 90536-47-3 SDF Download SDF
PubChem ID 102004592 Appearance Powder
Formula C9H10O4 M.Wt 182.2
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 1-(2,5-dihydroxy-3-methoxyphenyl)ethanone
SMILES CC(=O)C1=CC(=CC(=C1O)OC)O
Standard InChIKey IWEQNPUQLQPSJR-UHFFFAOYSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 2,5-dihydroxy-3-methoxy-Acetophenone

The roots of Euphorbia pekinensis Rupr.

Biological Activity of 2,5-dihydroxy-3-methoxy-Acetophenone

Description1. Acetophenones and chalcones may represent good leads in the discovery of new nematicidal compounds and may have potential use in crop management as active ingredients.
TargetsAntifection

2,5-dihydroxy-3-methoxy-Acetophenone Dilution Calculator

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2,5-dihydroxy-3-methoxy-Acetophenone Molarity Calculator

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Preparing Stock Solutions of 2,5-dihydroxy-3-methoxy-Acetophenone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.4885 mL 27.4424 mL 54.8847 mL 109.7695 mL 137.2119 mL
5 mM 1.0977 mL 5.4885 mL 10.9769 mL 21.9539 mL 27.4424 mL
10 mM 0.5488 mL 2.7442 mL 5.4885 mL 10.9769 mL 13.7212 mL
50 mM 0.1098 mL 0.5488 mL 1.0977 mL 2.1954 mL 2.7442 mL
100 mM 0.0549 mL 0.2744 mL 0.5488 mL 1.0977 mL 1.3721 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 2,5-dihydroxy-3-methoxy-Acetophenone

Nematicidal activity of acetophenones and chalcones against Meloidogyne incognita and structure-activity considerations.[Pubmed:25641877]

Pest Manag Sci. 2016 Jan;72(1):125-30.

BACKGROUND: With the ultimate goal of identifying new compounds active against root-knot nematodes, a set of 14 substituted chalcones were synthesised, starting from acetophenones. These chalcones and various acetophenones were tested in vitro against Meloidogyne incognita. RESULTS: The most potent acetophenones were 4-nitroacetophenone and 4-iodoacetophenone, with EC(50/24 h) values of 12 +/- 5 and 15 +/- 4 mg L(-1) respectively, somewhat weaker than that of the chemical control fosthiazate in our previous experiments (EC(50/24 h) 0.4 +/- 0.3 mg L(-1)). When we converted the acetophenones to chalcones, the nematicidal activity differed, based on their substitution pattern. The condensation of 4-nitroacetophenone with 2,4,6-trihydroxybenzaldehyde to give the corresponding chalcone (E)-1-(4-nitrophenyl)-3-(2,4,6-trihydroxyphenyl)prop-2-en-1-one led to a slight reduction in activity (EC(50/24 h) value 25 +/- 17 mg L(-1)). Moreover, (E)-3-(2-hydroxy-5-iodophenyl)-1-(4-methoxyphenyl)prop-2-en-1-one showed better activity (EC(50/24) h value 26 +/- 15 mg L(-1)) than 4-methoxyacetophenone (EC(50/24 h) value 43 +/- 10 mg L(-1)). CONCLUSIONS: Acetophenones and chalcones may represent good leads in the discovery of new nematicidal compounds and may have potential use in crop management as active ingredients.

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