Products with Phytoalexin bioactivity

Cat.No. Product Name
BCN4106 Isosativan
1. Isosativan, sativan and vestitol are isoflavan phytoalexins.
BCN4254 Moracin C
1. Moracin C and D, new phytoalexins from diseased mulberry, are antifungal compounds. 2. Moracin C has potent antibacterial activity, it can inhibit FabI and fatty acid synthesis, it inhibit S. aureus FabI with IC(50) of 83.8 uM. 3. Moracin C has anti-inflammatory effect, it can effectively reduce lipopolysaccharide (LPS) stimulated up-regulation of mRNA and protein expression of iNOS, COX-2, and serval pro-inflammatory cytokines (IL-1β, IL-6 and TNF-α. 4. Moracin may be protective influence in tumor promotion, utilization of Moracin may open a new avenue in the treatment of tumerigenesis.
BCN4255 Moracin D
1. Moracin C and moracin D, new phytoalexins from diseased mulberry, are antifungal compounds. 2. Moracin may be protective influence in tumor promotion, utilization of Moracin may open a new avenue in the treatment of tumerigenesis.
BCN4544 4'-Hydroxyacetophenone
4'-Hydroxyacetophenone is a potent xanthine oxidase inhibitor, three 4′-hydroxyacetophenone-related phytoalexins from Polymnia sonchifolia have antifungal activity.
BCN4585 2'-Hydroxydaidzein
1. 2'-Hydroxygenistein is an isoflavonoid phytoalexin. 2. 2'-Hydroxygenistein suppress chemical mediators in inflammatory cells, may have value in treatment and prevention of central and peripheral inflammatory diseases associated with excess production of chemical mediators. 3. 2'-Hydroxygenistein shows significant concentration-dependent inhibitory effects on the release of beta-glucuronidase and lysozyme from rat neutrophils in response to formyl-Met-Leu-Phe/cytochalasin B (fMLP/CB) with IC(50) values of 2.8+/-0.1 and 5.9+/-1.4 microM, respectively.

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