Products with Phytoalexin bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4592 | Broussonin A |
| 1. Broussonins A and B, new phytoalexins from diseased paper mulberry. 2. Broussonin A and nyasol suppress lipopolysaccharide (LPS)-stimulated inducible nitric oxide synthase (iNOS) expression at the transcriptional level through modulating NF-κB and down-regulation of the Akt and ERK signaling pathways. 3. Broussonin A shows estrogenic activity with ligand-binding activity of estrogen receptor, transcriptional activity of estrogen-responsive element-luciferase reporter genes. 4. Broussonin A can significantly inhibit adipocyte differentiation in 3T3-L1 cells as measured fat accumulation using Oil Red O assay. | |
| BCN4593 | Broussonin B |
| 1. Broussonins A and B, new phytoalexins from diseased paper mulberry. 2. Broussonin B can induce neurite outgrowth in PC-12 cells at concentration of 50 microg/ml, and show moderate inhibitory activities against a chymotrypsin-like activity of the proteasome. 3. Broussonin B can significantly inhibit adipocyte differentiation in 3T3-L1 cells as measured fat accumulation using Oil Red O assay. | |
| BCN4892 | (-)-Maackiain |
| (-)-Maackiain, a phytoalexin, which is an anti-allergic compound that suppresses the up-regulation of the histamine H1 receptor (H1R) gene. It shows significant growth inhibitory action on the growth of the human lymphoblastoid cell lines Molt and Raji, and shows a strong larvicidal effect against 4th instar larvae of Aedes aegypti(LC50=21.95±1.34ug/mL). | |
| BCN4898 | Encecalin |
| 1. Encecalin and demethylencecalin are major phytotoxic compounds isolated from Helianthella quinquenervis (Hook) A Gray (Asteraceae), they inhibit photosystem II (from water to 2,5-dibromo-3-methyl-6-isopropyl-1,4 p-benzo-quinone). 2. Encecalin and eupatoriochromene retard seed germination and reduce radicle and hypocotyl growth of weed and crop plant seedlings. | |
| BCN5199 | Sakuranetin |
| Sakuranetin, a flavanone phytoalexin from ultraviolet-irradiated rice leaves, it has antifungal, antimutagenic, anti-inflammatory and antioxidant effects, it shows a suppressive effect on umu gene expression of SOS response in Salmonella typhimurium TA1535/pSK1002 against the mutagen furylfuramide. Sakuranetin may contribute to maintain glucose homeostasis in animals, it can strongly induce differentiation of 3T3-L1 preadipocytes, stimulate glucose uptake in differentiated 3T3-L1 adipocytes.Sakuranetin stimulates melanogenesis in B16 melanoma cells via inhibition of ERK1/2 and PI3K/AKT signaling pathways, which lead to upregulation of Tyr, TRP1, and TRP2. | |
