Products with Skin-lightening agents bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN1215 | Chicoric acid |
| Chicoric acid, a new compound able to enhance insulin release and glucose uptake, it is a new potential antidiabetic agent carrying both insulin sensitizing and insulin-secreting properties. Chicoric acid has antiobesity effects, it can induce apoptosis in 3T3-L1 preadipocytes through ROS-mediated PI3K/Akt and MAPK signaling pathways. L-Chicoric acid has antiviral activity against HIV-1, which has been attributed to the inhibition of HIV-1 integration. | |
| BCN2576 | Aloin B |
| Dietary supplementation of aloe components (aloin, aloesin and aloe-gel) can ameliorate intestinal inflammatory responses in a 3% dextran sulfate sodium (DSS)-induced ulcerative colitis rat model, in particular, aloesin is the most potent inhibitor. The extract of A. vera and its active ingredient aloin cause melanin aggregation leading to skin lightening via alpha adrenergic receptor stimulation. | |
| BCN4309 | Artocarpin |
| 1. Artocarpin induces apoptosis in HSC-1 and T47D cells through modulation of MAPK and Akt/mTOR pathways, an extrinsic pathway , respectively . 2. Artocarpin has anti- bactericidal effect, can reduce the viability of pneumococci by a factor of >1000, without obvious harm to lung epithelial cells. 3. Artocarpin can prevent skin damage from UVB irradiation-induced photodamage in hairless mice and this is likely mediated through its antioxidant and anti-inflammation mechanisms. 4. Artocarpin possesses potent 5alpha reductase inhibitory effect. 5. Artocarpin has an efficient lightening effect on UV-stimulated hyperpigmented dorsal skins of brownish guinea pigs. | |
| BCN6248 | (+)-Lyoniresinol |
| 1. Lyoniresinol shows robust anti-melanogenic activity, decreases tyrosinase activity and melanin biosynthesis in B16F10 cells by activating ERK signaling, which downregulated MITF, tyrosinase, but not TRP-1 and TRP-2 protein expression. 2. Lyoniresinol has antioxidant effect. | |
| BCN6692 | Glabrene |
| Glabrene, Liquiritin apioside, neolicuroside, and 18β-glycyrrhetic acid are the predominant phenolic derivatives partitioning at the interface and most likely the major contributors to the notable synergistic antioxidant activity when coupled with pea protein hydrolysates (PPHs).Glabrene has estrogen-like activity, it can stimulate DNA synthesis in human endothelial cells (ECV-304; E304) and has a bi-phasic effect on proliferation of human vascular smooth muscle cells (VSMC). Glabrene and isoliquiritigenin may serve as candidates for skin-lightening agents, they exert varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis. | |
