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Citrus medica var. sarcodactylis

Citrus medica var. sarcodactylis

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Natural products/compounds from  Citrus medica var. sarcodactylis

  1. Cat.No. Product Name CAS Number COA
  2. BCN8517 Nerol106-25-2 Instructions
  3. BCN1034 Nomilin1063-77-0 Instructions
  4. BCN6057 Limonin1180-71-8 Instructions
  5. BCN5582 Bergapten484-20-8 Instructions
  6. BCN4831 Citropten487-06-9 Instructions
  7. BCN4993 Diosimin520-27-4 Instructions
  8. BCN4303 Obacunone751-03-1 Instructions

References

Citrus medica var. sarcodactylis (Foshou) activates fibroblast growth factor-2 signaling to induce migration of RSC96 Schwann cells.[Pubmed: 24707873]


Factors that enhance the intrinsic growth potential of neurons play a major role in the regeneration and repair of adult neurons following an injury. Fibroblast growth factor (FGF-2) is one of the key players in the origin and growth of neuronal and glial cells through autocrine and paracrine signaling. Water extract of Citrus medica var. sarcodactylis (fingered citron, foshou), which is been used effectively as a Chinese herbal medicine, was found to activate the FGF-2 promoter in transgenic luciferase expression models. Foshou treatment on Schwann cells (RSC96) transfected with luciferase reporter plasmid under a FGF-2 promoter was found to induce the FGF-2 promoter and showed enhanced luciferase expression. The FGF-2 expression was accompanied with an increase in the expression of proteins involved in cell migration and cell proliferation in a dose dependent manner. Therefore, foshou potentially enhances nerve regeneration by inducing the Schwann cell proliferation and migration.


[Studies on the chemical constituents of Citrus medica var. sarcodactylis].[Pubmed: 12451974]


Three compounds were isolated from Citrus medica L. var. sarcodactylis (Noot) Swingle. The structures were identified as limettin(I), stigmasta-5, 22-dien-3-ol(II) and palmilic acid(III) on the basis of UV, MS, IR, 1HNMR, 13CNMR and DEPT.


New cyclic peptides from Citrus medica var. sarcodactylis SWINGLE.[Pubmed: 12045349]


Two new cyclic peptides were isolated from the fruit peels of Citrus medica var. sarcodactylis SWINGLE. Their structures were elucidated as cyclo(-Gly-Asp-Leu-Thr-Val-Tyr-Phe-) and cyclo(-Gly-Leu-Pro-Trp-Leu-Ile-Ala-Ala-) by intensive two-dimensional (2D) NMR analysis and chemical evidence.