Natural Products from Citrus medica var. sarcodactylis
Natural Products Isolated from Citrus medica var. sarcodactylis
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- Natural product compounds selected from diverse chemical and biological sources.
- Broad structural diversity and coverage of biological activities.
- Product activity information can be supported by published literature, patents and research reports.
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Natural Products from Citrus medica var. sarcodactylis
7 natural product s associated with Citrus medica var. sarcodactylis
| Catalog No. | Product Name | CAS Number | COA |
|---|---|---|---|
| BCN5582 |
Bergapten
|
484-20-8 | COA |
| BCN4831 |
Citropten
|
487-06-9 | COA |
| BCN4993 |
Diosimin
|
520-27-4 | COA |
| BCN6057 |
Limonin
|
1180-71-8 | COA |
| BCN8517 |
Nerol
|
106-25-2 | COA |
| BCN1034 |
Nomilin
|
1063-77-0 | COA |
| BCN4303 |
Obacunone
|
751-03-1 | COA |
References
Citrus medica var. sarcodactylis (Foshou) activates fibroblast growth factor-2 signaling to induce migration of RSC96 Schwann cells.[Pubmed: 24707873]
Factors that enhance the intrinsic growth potential of neurons play a major role in the regeneration and repair of adult neurons following an injury. Fibroblast growth factor (FGF-2) is one of the key players in the origin and growth of neuronal and glial cells through autocrine and paracrine signaling. Water extract of Citrus medica var. sarcodactylis (fingered citron, foshou), which is been used effectively as a Chinese herbal medicine, was found to activate the FGF-2 promoter in transgenic luciferase expression models. Foshou treatment on Schwann cells (RSC96) transfected with luciferase reporter plasmid under a FGF-2 promoter was found to induce the FGF-2 promoter and showed enhanced luciferase expression. The FGF-2 expression was accompanied with an increase in the expression of proteins involved in cell migration and cell proliferation in a dose dependent manner. Therefore, foshou potentially enhances nerve regeneration by inducing the Schwann cell proliferation and migration.
[Studies on the chemical constituents of Citrus medica var. sarcodactylis].[Pubmed: 12451974]
Three compounds were isolated from Citrus medica L. var. sarcodactylis (Noot) Swingle. The structures were identified as limettin(I), stigmasta-5, 22-dien-3-ol(II) and palmilic acid(III) on the basis of UV, MS, IR, 1HNMR, 13CNMR and DEPT.
New cyclic peptides from Citrus medica var. sarcodactylis SWINGLE.[Pubmed: 12045349]
Two new cyclic peptides were isolated from the fruit peels of Citrus medica var. sarcodactylis SWINGLE. Their structures were elucidated as cyclo(-Gly-Asp-Leu-Thr-Val-Tyr-Phe-) and cyclo(-Gly-Leu-Pro-Trp-Leu-Ile-Ala-Ala-) by intensive two-dimensional (2D) NMR analysis and chemical evidence.