Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN6180 Heudelotinone
1. Heudelotinone shows cytotoxicity against three cancer cell lines A549, Hela, and SMMC-7721( IC50 values of 16.04, 10.67 and 21.68 uM , respectively).
BCN6181 Apigenin 4'-O-rhamnoside
1. Apigenin-4'-O-rhamnosylglucoside can strongly inhibit the classical pathway of the complement system.
BCN6184 Ponasterone A
1. Ponasterone A is insect moulting hormone. 2. Ponasterone A induced death of non-adapted insects may be related to PoA regulating different set of genes when compared to 20E.
BCN6186 4-Hydroxy-3,5-dimethoxybenzaldehyde
4-Hydroxy-3,5-dimethoxybenzaldehyde is an organic compound that occurs naturally in trace amounts, it possesses powerful antioxidant activity, in minimizing DNA damage, and activating survival signal Akt pathway, and it may be of value in the development of radioprotective compounds. It is used in pharmaceuticals, food, cosmetics, textiles, pulp and paper industries, and even in biological control applications.
BCN6187 Cudraxanthone L
1. Cudraxanthone L shows the significant hepatoprotective effect on nitrofurantoin-induced cytotoxicity in human liver-derived Hep G2 cells.
BCN6188 ent-3-Oxokaurane-16,17-diol
1. AKaurane-3,16,17-triol,ent-kaurane-3-oxo-16α,17-diol,and ent-16α,17-dihydroxyatisan-3-one are three kinds of toxic diterpenoids isolated from the roots of genus Euphorbia.
BCN6190 Koumine
Koumine shows potent anti-tumor, anxiolytic, antistress, antipsoriatic, and analgesic activities, it also protects against the development of arthritis in Rheumatoid arthritis (RA) animal models.Koumine can induce apoptosis of LoVo cells in a time-dependent manner and inhibit the DNA synthesis in LoVo cells, thereby blocking the cell cycle from G1 to S phase.
BCN6192 6-O-Caffeoylarbutin
1. 6'-O-caffeoylarbutin may serve as a skin-whitening ingredient with the merits of potent melanin inhibition,less toxicity and reversible melanin synthesis after stopping use.